Results 141 to 150 of about 378,954 (344)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Treatment outcomes of endoscopic submucosal dissection and surgery for colorectal neoplasms in patients with ulcerative colitis

, 2021
Kengo Kasuga, Masayoshi Yamada, Dai Shida, Teppei Tagawa, Hiroyuki Takamaru, Masau Sekiguchi, Taku Sakamoto, Toshio Uraoka, Shigeki Sekine, Yukihide Kanemitsu, Yutaka Saito   +10 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Novel Method for Screening Colorectal Neoplasm

EBioMedicine, 2015
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide with the majority of cases having no previous family history. The most effective way to reduce mortality is to detect precancerous adenoma in an early stage. Several screening methods are now available; however as each modality has its limitation there is no superb strategy ...
openaire   +3 more sources

Key performance indicators for the National Bowel Cancer Screening Program: technical report [PDF]

Provides a summary of the development process and the technical specification for the 11 agreed performance indicators that are part of the National Bowel Cancer Screening Program Performance Indicator Set.

core  

Liver resection for metastatic colorectal cancer [PDF]

, 1986
From 1975 to 1985, 60 patients with isolated hepatic metastases from colorectal cancer were treated by 17 right trisegmentectomies, five left trisegmentectomies, 20 right lobectomies, seven left lobectomies, eight left lateral segmentectomies, and three ...
Esquivel, CO, Gordon, RD, Iwatsuki, S, Starzl, TE   +3 more
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Caracterización de pacientes operados de cáncer colorrectal en el hospital “Guillermo Domínguez López”

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2020
Fundamento: en el municipio Puerto Padre han ido aumentando paulatinamente los pacientes con el diagnóstico de cáncer de colon y recto.Objetivo: caracterizar a los pacientes operados de cáncer colorrectal en el servicio de cirugía del hospital “Guillermo
Jorge Luis Montes-de-Oca-Mastrapa, Adriana de la Caridad Cera-Gisbert   +1 more
doaj  

Artificial intelligence for the prevention and prediction of colorectal neoplasms. [PDF]

J Transl Med, 2023
Tokutake K, Morelos-Gomez A, Hoshi KI, Katouda M, Tejima S, Endo M.   +5 more
europepmc   +1 more source

Interaction of Colorectal Neoplasm Risk Factors and Association with Metabolic Health Status Focusing on Normal Waist-to-Hip Ratio in Adults [PDF]

Ying‐Chun Lin, Hung-Ju Ko, Lo‐Yip Yu, Ming-Jen Chen, Horng‐Yuan Wang, Shou-Chuan Shih, Chuanchuan Liu, Yang‐Che Kuo, Kuang‐Chun Hu   +8 more
openalex   +1 more source