Results 151 to 160 of about 699,211 (296)

Colorectal Cancer Stat Bite

From 2015 to 2019, about 1 in 3 colorectal cancer cases were diagnosed at a localized stage, meaning the cancer had not spread outside the colon or rectum.64% of colorectal cancer patients who were diagnosed from 2012 to 2018 had not died from their ...

core  

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

The comparison of risk factors for colorectal neoplasms at different anatomical sites. [PDF]

Int J Colorectal Dis, 2023
Wang H, Yuan Z, Wang S, Pang W, Wang W, Liu X, Yi B, Han Q, Yao Y, Zhang Q, Zhang X, Zhang C.   +11 more
europepmc   +1 more source

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

Advanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun, Hengjie Xu, Sheng Yang, Jiahui Zhou, Chuanxin Tian, Hongxu Nie, Chi Jin, Tuo Wang, Zhihao Chen, Junwei Tang, Yifei Feng, Xiaowei Wang, Yueming Sun   +12 more
wiley   +1 more source

Endoscopic Submucosal Dissection for Colorectal Neoplasms: Is the West Catching Up? [PDF]

Cancers (Basel)
Vohra I, Gopakumar H, Meyyappan A, Chen C, Blatter G, Martins B, Thakkar S, Sharma N.   +7 more
europepmc   +1 more source

Smoking as a risk factor for colorectal neoplasms in young individuals? A systematic meta-analysis. [PDF]

Int J Colorectal Dis, 2023
Li Q, Weitz J, Li C, Schardey J, Weiss L, Wirth U, Zimmermann P, Bazhin AV, Werner J, Kühn F.   +9 more
europepmc   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Fish Consumption and Colorectal Neoplasms among Lynch Syndrome Carriers. [PDF]

J Nutr
Bulbaai MT, Wesselink E, Bisseling TM, Koornstra JJ, van Leerdam ME, Le Marchand L, Newcomb PA, Samadder NJ, Schep-Wijnveen HJ, Kampman E, van Duijnhoven FJ.   +10 more
europepmc   +1 more source

Ferroptosis Suppression by the M6A Reader IGF2BP1 Underlies Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu, Yue Huang, Jing‐Yuan Ye, Si‐Yuan Lu, Zhi‐De Liu, Ming‐Jian Ma, De‐Liang Fang, Zi‐Yi Zhao, Jin‐Zhao Xie, Jiao Chen, Xiao‐Yu Yin   +10 more
wiley   +1 more source

A Multicenter Prospective Protocol to Explore the Relationship Between <i>Enterococcus faecalis</i> Bloodstream Infections and Colorectal Neoplasms (EnteroColonus-GAMES Project). [PDF]

Microorganisms
Pericàs JM, Cañas MA, Goenaga MA, Nevado C, Kestler M, De La Villa S, Muñoz P, Blanes R, Tasias M, Escudero-Sánchez R, Moreno-García J, Alonso-Socas MM, Rodríguez-Esteban Á, Calderón-Parra J, Diego-Yagüe I, Boix-Palop L, García-Álvarez L, Gasch O, Careta O, Paredes R, Luzko IS, Garcia-De-La-Mària C, Hernández-Meneses M, Cuervo G, Moreno A, Arias CA, Miró JM, EnteroColonus GAMES Investigators.   +27 more
europepmc   +1 more source