METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang+8 more
wiley +1 more source
Single dose aspirin affects fecal immunohistochemical test sensitivity in detecting advanced colorectal neoplasms: Truth or expectation? [PDF]
Yonca Yılmaz Ürün, Selim Aydemir
openalex +1 more source
USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang+13 more
wiley +1 more source
Implementation of Synoptic Reporting for Endoscopic Localization of Complex Colorectal Neoplasms. [PDF]
Roy H+6 more
europepmc +1 more source
Treatment outcomes of endoscopic submucosal dissection and surgery for colorectal neoplasms in patients with ulcerative colitis. [PDF]
Kasuga K+10 more
europepmc +1 more source
Current research status of endoscopic submucosal dissection for colorectal neoplasms
Chen Huang+3 more
openalex +2 more sources
Thin-probe endoscopic ultrasonography for surgical resection of early colorectal neoplasms: A pilot study [PDF]
Hideo Yanai+3 more
openalex +1 more source
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu+20 more
wiley +1 more source
Response to the commment of changes of endotracheal tube cuff pressure and its indicators in laparoscopic resection of colorectal neoplasms: an observational prospective clinical trial: BMC anesthesiology. 2024 Nov 13;24(1):413. [PDF]
Wang X+6 more
europepmc +1 more source