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Metabolomics Biomarkers for Detection of Colorectal Neoplasms: A Systematic Review [PDF]
Cancers, 2018 Background: Several approaches have been suggested to be useful in the early detection of colorectal neoplasms. Since metabolites are closely related to the phenotype and are available from different human bio-fluids, metabolomics are candidates for non ...
, Petra KING, Megha Bhardwaj
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Postgraduate Medicine, 1995
Colorectal cancer is a very important cause of death and disability throughout the world. In the future, it may be possible to reduce the risk of this disease through such measures as dietary modification or use of aspirin or other nonsteroidal anti-inflammatory drugs, but this remains to be proved.
J A, Truszkowski, R W, Summers
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Colorectal cancer is a very important cause of death and disability throughout the world. In the future, it may be possible to reduce the risk of this disease through such measures as dietary modification or use of aspirin or other nonsteroidal anti-inflammatory drugs, but this remains to be proved.
J A, Truszkowski, R W, Summers
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Flat and depressed colorectal neoplasms
Current Opinion in Gastroenterology, 2003An increasing body of literature is available showing the existence of flat and depressed colorectal neoplasms in Western countries. The appreciation that colorectal neoplasms may present as flat or depressed lesions has important implications, as the risk of adenocarcinoma in depressed lesions has been found to be markedly higher than in flat or ...
Roy M, Soetikno +3 more
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Laparoscopic surgery for colorectal neoplasms
Seminars in Surgical Oncology, 1994AbstractLaparoscopy is being used to assist in an increasing number and variety of bowel procedures. However, when being used for neoplastic disease concerns of margins and adequacy of mesenteric dissection must be addressed. We've performed 110 laparoscopic‐assisted bowel procedures, with 45 of these performed for neoplastic disease.
W L, Ambroze +4 more
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Origins and morphogenesis of colorectal neoplasms
APMIS, 1999Gastrointestinal stem cells are considered pivotal in colonic carcinogenesis. There is evidence to suggest that early microadenomas in the colon are polyclonal in origin. Adenomas, once initiated, enlarge by the process of crypt fission. It is also the main mechanism by which neoplastic clones spread through the colorectal epithelium. Both concepts are
W M, Wong, S B, Garcia, N A, Wright
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Prevention and Chemoprevention of Colorectal Neoplasms
Digestive and Liver Disease, 2002Main purpose of the review is to analyse the impact of the current approaches for colorectal cancer prevention, including chemoprevention. Available evidence does not support the contention that a more appropriate diet can be of great help in the prevention of these neoplasms, either because the scientific evidence is poor and highly controversial, or ...
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Screening for Colorectal Neoplasms
2009Evidence is mounting that colorectal adenocarcinoma can be prevented by detecting and removing adenomatous polyps, and that detecting early-stage cancers reduces mortality from the disease. Both polyps and early-stage cancers are usually asymptomatic; cancers that have grown large enough to cause symptoms have a much worse prognosis.
David E. Beck +4 more
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2014
Abstract Colorectal cancer is primarily a disease of urban, industrialized societies. In the United States, the lifetime risk for the development of this cancer is approximately 6%. Recent data have suggested that the incidence rates for colorectal cancer may be decreasing gradually in some subgroups of the population.
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Abstract Colorectal cancer is primarily a disease of urban, industrialized societies. In the United States, the lifetime risk for the development of this cancer is approximately 6%. Recent data have suggested that the incidence rates for colorectal cancer may be decreasing gradually in some subgroups of the population.
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Prevalence of Colorectal Neoplasms in Asian Americans
Digestive Diseases and Sciences, 2008To determine the yield of colonoscopy in a predominantly Asian American gastroenterology practice in California from 8/2003 to 2/2005.A total 2,723 subjects were included: 87% were Asian and 13% were non-Asian. Advanced neoplasia prevalence was 12% in Asian men and 9% in non-Asian men (P = 0.21), and 8% and 7% in women (P = 0.62).
Khoa D, Lam +9 more
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Chemoprevention of Colorectal Neoplasms
Archives of Surgery, 1986The organospecific, 1,2-dimethylhydrazine-induced rat tumor model was used to test tumor formation in groups of animals receiving regular chow, powdered chow with 7%/wt ascorbic acid supplement, pelleted chow with 1%/wt beta-carotene supplement, and pelleted chow with placebo beadlets. Following a 16-week induction period, animals were killed and tumor
T A, Colacchio, V A, Memoli
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