The clinical significance of vitamin D levels and vitamin D receptor mRNA expression in colorectal neoplasms. [PDF]
Fang Y, Song H, Huang J, Zhou J, Ding X.
europepmc +1 more source
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
Ulcerative colitis-associated colorectal neoplasm is increasing as a surgical indication in the biologics era: a retrospective observational study of 20 years of experience in a single tertiary center [PDF]
Hyo Jun Kim +7 more
openalex +1 more source
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang +17 more
wiley +1 more source
Endoscopic full thickness resection (EFTR) of colorectal neoplasms with the Full Thickness Resection Device (FTRD): Clinical experience from two tertiary referral centers in Switzerland [PDF]
Patrick Aepli +4 more
openalex +1 more source
This study shows anti‐CEACAM5 CAR T‐cells are ineffective against colorectal cancer (CRC) because of CEACAM5 sequestration at intercellular junctions and the thick tumour cell glycocalyx. Enzymatic treatments of CRC cell monolayer/tissue section with trypsin or hyaluronidase restore CEACAM5 availability, enhance CAR T‐cell activation, increase ...
Debasis Banik +13 more
wiley +1 more source
Changes of endotracheal tube cuff pressure and its indicators in laparoscopic resection of colorectal neoplasms: an observational prospective clinical trial. comment on: BMC anesthesiology. 2024 Nov 13;24(1):413. [PDF]
Maxwell A.
europepmc +1 more source
Expression and promoter methylation of AREG in colorectal neoplasms
Tao Wu +6 more
openalex +1 more source
The changing face of hepatic resection [PDF]
Iwatsuki, S, Sheahan, DG, Starzl, TE
core +1 more source

