Results 251 to 260 of about 366,130 (353)

Metabolic Syndrome and Colorectal Neoplasm

, 2012
Tsai‐Chung Li, Cheng‐Chieh Lin
openalex   +1 more source

Development and validation of a scoring system for advanced colorectal neoplasm in young Korean subjects less than age 50 years [PDF]

, 2018
Ji Yeon Kim, Sungkyoung Choi, Taesung Park, Seul Ki Kim, Yoon Suk Jung, Jung Ho Park, Hong Joo Kim, Yong Kyun Cho, Chong Il Sohn, Woo Kyu Jeon, Byung Ik Kim, Kyu Yong Choi, Dong Il Park   +12 more
openalex   +1 more source

GSK461364 Inhibits NLRP3 Inflammasome by Targeting NEK7 Phosphorylation

Advanced Science, EarlyView.
Schematic diagram of the mechanism by which GSK461364 inhibits NLRP3 inflammasome activation. GSK461364 inhibits the phosphorylation of NEK7 likely at serine 221 and serine 260 by suppressing the activity of PLK1, thereby restraining the formation of the NLRP3 inflammasome.
Ruiheng Luo, Mingliang Ma, Dan Wang, Ling Luo, Xueming Xu, Lingmin Huang, Fupeng Wang, Guangyan Kuang, Huiqi Liu, Rui Ni, Xin Li, Qinghua Zhang, Shengfeng Wang, Kai Zhao   +13 more
wiley   +1 more source

An Adjustable Positivity Threshold for Non-invasive Screening Tests for Colorectal Neoplasms Can Improve Screening Program Effectiveness and Feasibility. [PDF]

Dig Dis Sci
Young GP, Senore C, Schoengold R, Laven-Law G, Saito H, Symonds EL.   +5 more
europepmc   +1 more source

Derivation and validation of a prediction rule for estimating colorectal neoplasm risk in asymptomatic individuals in southern Jiangsu province

, 2013
Guochang Chen, Boneng Mao, Qian Liu, Ji Qian, Lei Liu   +4 more
openalex   +1 more source

Hypoxia‐Induced circPRELID2 Promotes Gastric Cancer Metastasis by Facilitating ZEB2 Translation via PCBP1 O‐GlcNAcylation

Advanced Science, EarlyView.
Under hypoxia, HIF1A is directly bound to the PRELID2 promoter to increase PRELID2 pre‐mRNA expression, followed by the DYRK1A–SFPQ–SAM68 complex binding to Alu‐containing introns in PRELID2 pre‐mRNA, leading to circPRELID2 circularization. CircPRELID2 interacts with PCBP1 and promotes its cytoplasmic retention.
Pengshan Zhang, Zai Luo, Yitian Xu, Yuan Zhang, Renchao Zhang, Nadina Paerhati, Shaopeng Zhang, Qianqian Cai, Zhengjun Qiu, Chen Huang   +9 more
wiley   +1 more source

Nine-fold variation of risk of advanced colorectal neoplasms according to smoking and polygenic risk score: Results from a cross-sectional study in a large screening colonoscopy cohort. [PDF]

Cancer Commun (Lond)
Fu R, Chen X, Niedermaier T, Seum T, Hoffmeister M, Brenner H.   +5 more
europepmc   +1 more source

Men with negative results of guaiac‐based fecal occult blood test have higher prevalences of colorectal neoplasms than women with positive results

, 2013
Hermann Brenner, Michael Hoffmeister, Berndt Birkner, Christian Stock   +3 more
openalex   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

Advanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez, Maria Virginia Giolito, Sultan Al‐Siyabi, Kristian Serafimov, Florine Laloux, Emeline Dierge, Léo Aubert, Céline Guilbaud, Selena Kaye, Paula Varon, Dorothée Marchand, Hanne Vlieghe, Emmanuel Hermans, Caroline Bouzin, Davide Brusa, Christiani Andrade Amorim, Barabara Pachikian, Yvan Larondelle, Cyril Corbet, Chantal Dessy, Olivier Feron   +20 more
wiley   +1 more source

Colonoscopy plays an important role in detecting colorectal neoplasms in patients with gastric neoplasms. [PDF]

World J Gastrointest Oncol
Liu XR, Wen ZL, Liu F, Li ZW, Liu XY, Zhang W, Peng D.   +6 more
europepmc   +1 more source