Results 261 to 270 of about 366,130 (353)

Human medicines European public assessment report (EPAR): Zirabev, bevacizumab, Colorectal Neoplasms,Breast Neoplasms,Carcinoma, Non-Small-Cell Lung,Carcinoma, Renal Cell,Uterine Cervical Neoplasms, Date of authorisation: 14/02/2019, Revision: 1, Status: Authorised [PDF]

, 2019

openalex   +1 more source

SURGICAL NANAGEMENT OF COLORECTAL NEOPLASMS

The Japanese Journal of Gastroenterological Surgery, 1981
openaire   +3 more sources

SURF: A Self‐Supervised Deep Learning Method for Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Science, EarlyView.
SURF is a robust reference‐free deconvolution tool that integrates high‐dimensional spatial transcriptomics gene expression analysis with self‐supervised deep learning, enabling effective modeling of non‐linear gene interactions and spot relationships.
Shuyu Liang, Zixia Zhou, Peng Huang, Junhu Fu, Jing Jiao, Yunxia Huang, Shichong Zhou, Guanlin Wang, Yuanyuan Wang, Yi Guo   +9 more
wiley   +1 more source

Megasphaera Elesdenii Dysregulates Colon Epithelial Homeostasis, Aggravates Colitis‐Associated Tumorigenesis

Advanced Science, EarlyView.
A fecal microbial meta‐analysis reveals that Megasphaera is highly abundant in the Asian population with IBD and CRC. M. elsdenii reshapes colonic immunity by triggering DC cell‐mediated Th1 and Th17 inflammation. M. elsdenii and M. elsdenii‐enriched microbiota exacerbate colonic inflammation and tumorigenesis in AOM/DSS mice.
Xinxin Hou, Zhaozhou Zhang, Wanqing Chen, Jinming Li, Xiangxiang Zhu, Mingjie Li, Xiaoqi Guan, Haidong Guo, Yanlei Ma, Ling Zhao   +9 more
wiley   +1 more source

Pokemon inhibits Bim transcription to promote the proliferation, anti-anoikis, invasion, histological grade, and dukes stage of colorectal neoplasms. [PDF]

J Cancer Res Clin Oncol
Wang Y, Zeng H, Li L, Liu J, Lin J, Bie Y, Wang S, Cheng X, Nashun B, Yao Y, Hu X, Zhao Y.   +11 more
europepmc   +1 more source

Apolipoprotein E Polymorphism and Colorectal Neoplasm: Results from a Meta-Analysis

, 2014
Yun Tian, Jirong Wang, Ying Ye, Liqun Sun, Yingrui Fan, Li Wang, Juan Li, Zhaoxia Wang, Ke‐Ming Wang   +8 more
openalex   +2 more sources

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Osteoporosis Is Associated with an Increased Risk of Colorectal Neoplasms Regardless of Sex: Nationwide Population-Based Cohort Study. [PDF]

Diagnostics (Basel)
Yoo SH, Nam JH, Oh DJ, Park GU, Kim SH, Kang HW, Kim JH, Lim YJ.   +7 more
europepmc   +1 more source

Mo1912 The Prevalence of Colorectal Adenomas and Advanced Neoplasms Detected Through PAN-Chromocolonoscopy in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD). A Prospective Study

, 2014
Alina Tanțău, Marcel Tanţău
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PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

Advanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu, Li‐Kun Ren, Xiao‐Bin Fei, Song‐Bai Liu, Yong‐Jia Gao, Jun‐Yi Hou, Chi Wang, Peng Liu, Chang‐Hao Zhu, Xing Wang, Yao‐Zhen Pan   +10 more
wiley   +1 more source