Results 261 to 270 of about 252,921 (351)

The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism

Advanced Science, EarlyView.
The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino, Marianna Avitabile, Vincenzo Aievola, Annalaura Montella, Vito A. Lasorsa, Ferdinando Bonfiglio, Mariagrazia Cantalupo, Sueva Cantalupo, Gilda Estinto, Matilde Tirelli, Martina Morini, Martina Ardito, Alessandra Eva, Vincenza Cerbone, Lucia Mauriello, Marianna Caterino, Margherita Ruoppolo, John M. Maris, Sharon J. Diskin, Achille Iolascon, Mario Capasso   +20 more
wiley   +1 more source

Apolipoprotein E Polymorphism and Colorectal Neoplasm: Results from a Meta-Analysis

, 2014
Yun Tian, Jirong Wang, Ying Ye, Liqun Sun, Yingrui Fan, Li Wang, Juan Li, Zhaoxia Wang, Ke‐Ming Wang   +8 more
openalex   +2 more sources

POLE Deficiency Exacerbates Diesel Engine Exhaust‐Induced Genomic Instability and Malignant Transformation of Bronchial Epithelial Cells

Advanced Science, EarlyView.
This study establishes a diesel engine exhaust (DEE)‐induced malignant transformation model in bronchial epithelial cells. Whole genome sequencing（WGS） and RNA‐seq reveal DEE‐induced mutational signatures and gene expression profiles. Mechanistically, DEEaffect polymerase epsilon (POLE) and mismatch repair, driving genomic instability and promoting ...
Pimei Zhang, Zhaoxu Wu, Qiang Ju, Nuo Xu, Xian Chen, Hongguang Chen, Shuaishuai Yang, Jing Ji, Yanjie Zhao   +8 more
wiley   +1 more source

Osteoporosis Is Associated with an Increased Risk of Colorectal Neoplasms Regardless of Sex: Nationwide Population-Based Cohort Study. [PDF]

Diagnostics (Basel)
Yoo SH, Nam JH, Oh DJ, Park GU, Kim SH, Kang HW, Kim JH, Lim YJ.   +7 more
europepmc   +1 more source

Mo1912 The Prevalence of Colorectal Adenomas and Advanced Neoplasms Detected Through PAN-Chromocolonoscopy in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD). A Prospective Study

, 2014
Alina Tanțău, Marcel Tanţău
openalex   +1 more source

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source

Effect of cuff inflation with lidocaine, saline, and air on tracheal tube cuff pressure during laparoscopic resection of colorectal neoplasms: a randomized clinical trial. [PDF]

BMC Anesthesiol
Wang X, Zhang J, Zhu G, Cai S, Zhang Q, Duan M, Feng S.   +6 more
europepmc   +1 more source

Comparative Analysis of Clinical Outcomes and Financial Aspects of Phototherapies and Immunotherapy for Cancer

Advanced Science, EarlyView.
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan, Kun Shao, Roopa Hebbandi Nanjundappa, Daniel‐Jiajun Yu, Marianne Stanford, Huile Gao, Channakeshava Sokke Umeshappa   +6 more
wiley   +1 more source

Immunohistochemical and molecular characterizations in urothelial carcinoma of bladder in patients less than 45 years [PDF]

, 2017
Dehner, Louis P, et al,
core   +1 more source

Metabolic syndrome and colorectal neoplasms: An ominous association

, 2015
Daniel Trabulo
openalex   +1 more source