Results 51 to 60 of about 699,211 (296)

Effects of supplemental vitamin D and calcium on markers of proliferation, differentiation, and apoptosis in the normal colorectal mucosa of colorectal adenoma patients.

PLoS ONE, 2018
To clarify the roles of vitamin D and calcium as potential chemopreventive agents against colorectal cancer in humans, and to develop "treatable", pre-neoplastic, phenotypic biomarkers of risk for colorectal neoplasms, we estimated the effects of ...
Yasheen Gao, Caroline Y Um, Veronika Fedirko, Robin E Rutherford, March E Seabrook, Elizabeth L Barry, John A Baron, Roberd M Bostick   +7 more
doaj   +1 more source

Clinicopathological characteristics of colorectal intraepithelial neoplasms in AN+SP and AN-only groups.

, 2014
Clinicopathological characteristics of colorectal intraepithelial neoplasms in AN+SP and AN-only groups.
Takahiro Horimatsu (319487), Manabu Muto (223899), Ajay Goel (130080), Atsushi Yamada (282892), Sachiko Minamiguchi (567114), Tsutomu Chiba (170849), Yoshiharu Sakai (567115), C. Richard Boland (130077)   +7 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Screen for Life: National Colorectal Cancer Action Campaign 2012 year end report [PDF]

The Centers for Disease Control and Prevention\u2019s (CDC) Screen for Life: National Colorectal Cancer Action Campaign (SFL) is a multiyear, multimedia initiative to educate men and women aged 50 years and older\u2014the age group at greatest risk of ...

core   +2 more sources

The ability of HALP score to distinguish between malignant and benign colorectal neoplasms and its prognostic importance in colorectal cancers

Medicine Science, 2023
Systemic inflammation and nutritional status play important roles in the development and progression of various cancers, including colorectal cancer. The prognosis for malignancies can be predicted using the inflammatory marker known as HALP (calculated ...
Ibrahimhalil Dusunceli, Zeynep Gok Sargin, Umut Celik, Fatih Sargin   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Effects of antithrombotic drugs on the results of fecal immunochemical test in colorectal neoplasms screening

Scientific Reports, 2021
Fecal immunochemical test (FIT) is widely used as a colorectal cancer screening tool. Antithrombotic drugs may affect the screening performance of FIT for colorectal tumors.
Takashi Ibuka, Seiji Adachi, Yohei Horibe, Tomohiko Ohno, Masatoshi Mabuchi, Yusuke Suzuki, Osamu Yamauchi, Eri Takada, Midori Iwama, Koshiro Saito, Masamichi Arao, Koji Takai, Hiroshi Araki, Masahito Shimizu   +13 more
doaj   +1 more source

Association of cigarette smoking with risk of colorectal cancer subtypes classified by gut microbiota

Tobacco Induced Diseases, 2023
Introduction Both cigarette smoking and gut microbiota play important roles in colorectal carcinogenesis. We explored whether the association between smoking and colorectal cancer (CRC) risk varies by gut microbial enterotypes and how smoking-related ...
Jia-An Cai, Yong-Zhen Zhang, En-Da Yu, Wei-Qun Ding, Zhao-Shen Li, Liang Zhong, Quan-Cai Cai   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Association of modifiable risk factors and telomere length with five neuroendocrine neoplasms: a bidirectional Mendelian randomization study

Discover Oncology
Background  The timely recognition of modifiable risk factors holds paramount importance in tumor prevention. We aimed to scrutinize the causal relationships between a spectrum of genetically modifiable risk factors and five distinct neuroendocrine ...
Xujia Li, Lingli Huang, Yue Yan, Yuming Rong, Xuxian Chen, Mengge Gao, Jinsheng Huang   +6 more
doaj   +1 more source