Results 91 to 100 of about 3,282,422 (392)

Finite element model set-up of colorectal tissue for analyzing surgical scenarios [PDF]

, 2017
Finite Element Analysis (FEA) has gained an extensive application in the medical field, such as soft tissues simulations. In particular, colorectal simulations can be used to understand the interaction with the surrounding tissues, or with instruments ...
Bici, Michele, Bini, Fabiano, Campana, Francesca, Guachi, Robinson, Marinozzi, Franco   +4 more
core   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

The comparison of an accessible C-shaped partial stapled hemorrhoidopexy (C-PSH) versus circular stapled hemorrhoidopexy (CSH) in patients with grade IV hemorrhoids: a retrospective cohort study

BMC Gastroenterology, 2023
Objectives The objectives of this study were to present an accessible C-shaped partial stapled hemorrhoidopexy (C-PSH) in the treatment of grade IV hemorrhoids and to assess long-term outcomes of this technique compared with circular stapled ...
Jun He, Meng-Dan Zhou, Wen-Jing Wu, Zhi-Yong Liu, Dong Wang, Guan-Gen Yang, Qin-Yan Yang, Zhong Shen   +7 more
doaj   +1 more source

Colorectal Surgery [PDF]

Indian Journal of Surgery, 2015
It is a great privilege to write a review for a book on Colorectal Surgery edited by Dr. Prabin B. Thapa and Dr. Dhiresh K. Maharjan. The book provides comprehensive information about many aspects of colorectal surgery. It also includes the surgical anatomy and its relevance in total mesorectal excision (TME).
openaire   +1 more source

SP1.2.4A Single Centre experience in Robot-assisted Colorectal Surgery: First 70 cases [PDF]

, 2021
William Rea, Sandeep Singh, Shaun Nai, Neil Kukreja, Hendrik Wegstapel   +4 more
openalex   +1 more source

Factors influencing choice of chemotherapy in metastatic colorectal cancer (mCRC) [PDF]

, 2013
Management of metastatic colorectal cancer requires a multimodal approach and must be performed by an experienced, multidisciplinary expert team. The optimal choice of the individual treatment modality, according to disease localization and extent, tumor
BASSO, ENRICO, CARUSO, DAVIDE, EVANGELISTA, SALVATORE, Foteini Vakiarou, G. Rinaldi, L. Bianchi, Lo Russo, Giuseppe, PAPA, ANSELMO, Perrone-congedi, Francesca, PRETE, ALESSANDRA ANNA, ROSSI, Luigi, SPINELLI, GIAN PAOLO, Stati, Valeria, TOMAO, SILVERIO, VERRICO, MONICA, ZORATTO, federica   +15 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Attitudes of surgeons to the use of postoperative markers of the systemic inflammatory response following elective surgery [PDF]

, 2017
Background: Cancer is responsible for 7.6 million deaths worldwide and surgery is the primary modality of a curative outcome. Postoperative care is of considerable importance and it is against this backdrop that a questionnaire based study assessing ...
Dolan, Ross D., Horgan, Paul G., McMillan, Donald C., McSorley, Stephen T.   +3 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Impact and evolution of minimal invasive surgery in a centralized colorectal service: trends, safety and oncological outcomes across 15 years

World Journal of Surgical Oncology
Aim Specialization with subsequent evolving minimally invasive surgery (MIS) has been increasingly adopted in colorectal cancer care. This study aims to evaluate the impact of centralization and team specialization on oncologic quality and patient safety
Ali Toffaha, Mahmood Al-Dhaheri, Sherif Ahmed, Ayman Ahmed, Ibrahim Amer, Mahwish khawar, Ammar Aleter, Ejaz Latif, Hamza A. Abdul-Hafez, Salwa Ahmed, Mohammed Yousif, Noof Al Naimi, Mohamed A. Kurer, Amjad Parvaiz, Mohamed Abunada   +14 more
doaj   +1 more source