Results 101 to 110 of about 1,849,576 (300)

Self‐Sustaining Lactate Depletion Nanoplatform Remodels Tumor Microenvironment and Augments Synergistic Photodynamic/Photothermal/Chemodynamic/Starvation Therapy for Eradication of Colon Cancer

Advanced Science, EarlyView.
The HILA nanoplatform integrates HMnO2, LOX, and ICG to orchestrate multimodal therapy (starvation, chemodynamic, photodynamic, and photothermal) for achieving efficient colon cancer eradication. The established HMnO2‐LOX catalytic cycle continuously consumes lactate, acidifys microenvironment, relieves hypoxia, and generats reactive oxygen species ...
Yu‐E. Wang, Shibo Zhao, Wenying Wu, Zhiwei Duan, Yuan Li, Xiangyu Zeng, Liang Hong, Yan Chen, Ling Tao, Kewu Zeng, Chaoda Xiao, Xiangchun Shen   +11 more
wiley   +1 more source

Case report: Coexistence of rectal signet ring cell carcinoma with neuroendocrine components

BMC Geriatrics
Background Signet ring cell carcinoma is a rare histological type among the various forms of colorectal cancers. Even rare is when it coexisted with neuroendocrine components in one tumor.
Ling Xu, Zhefeng He, Chao Fu, Yiyang Wu, Anwei Wu, Guojiang Tian, Jianfei Huang, Xibo Liu, Qi Wang   +8 more
doaj   +1 more source

Outcomes of Robotic-Assisted Colorectal Surgery Compared with laparoscopic and Open Surgery: a Systematic Review

, 2014
BACKGROUND: Robotic technology has been applied to colorectal surgery over the last decade. The aim of this review is to analyze the outcomes of robotic colorectal surgery systematically and to provide objective information to surgeons.
백승혁, 김창우, 김창희
core   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

Postoperative outcomes after prehabilitation for colorectal cancer patients undergoing surgery: a systematic review and meta-analysis of randomized and nonrandomized studies [PDF]

Annals of Coloproctology
Purpose Prehabilitation (PH) is purported to improve patients’ preoperative functional status. This systematic review and meta-analysis sought to compare short-term postoperative outcomes between patients who underwent a protocolized PH program and the ...
Ian Jun Yan Wee, Isaac Seow-En, Aik Yong Chok, Eileen Sim, Chee Hoe Koo, Wenjie Lin, Chang Meihuan, Emile Kwong-Wei Tan   +7 more
doaj   +1 more source

Epidural analgesia and mortality after colorectal cancer surgery : A retrospective cohort study

, 2021
Background: Epidural analgesia (EA) has been the standard of care after major abdominal surgery for many years. This study aimed to correlate EA with postoperative complications, short- and long-term mortality in patients with and without EA after open ...
Forssten, Maximilian Peter, Mohseni, Shahin,, Bass, Gary Alan,, Gupta, Anil,, Hjelmqvist, Hans, Falk, Wiebke, Matthiessen, Peter, Bass, Gary Alan, Falk, Wiebke,, Gupta, Anil, Mohseni, Shahin, Hjelmqvist, Hans,, Forssten, Maximilian Peter,, Matthiessen, Peter,   +13 more
core   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Outcomes of Subtotal Colectomy with Ileorectal Anastomosis and Intensive Endoscopic Surveillance in Familial Adenomatous Polyposis: A Case Series

Cancer Management and Research
Chi-Han Yang,1 Hsiang-Lin Tsai,1,2 Yen-Cheng Chen,1– 3 Po-Jung Chen,1,3 Tsung-Kun Chang,1,3,4 Wei-Chih Su,1,3,4 Ching-Wen Huang,1,2 Jaw-Yuan Wang1– 3,5– 7 1Division of Colorectal Surgery, Department of Surgery, Kaohsiung Medical University Hospital ...
Yang CH, Tsai HL, Chen YC, Chen PJ, Chang TK, Su WC, Huang CW, Wang JY   +7 more
doaj  

Study protocol for BeWEL: The impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas [PDF]

, 2011
Background: Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second highest cause of cancer death in the UK. Most cases occur in people over 50 years and CRC often co-exists with other lifestyle related disorders including ...
Belch, Jill J F, Steele, RJC, Anderson, Annie, Steele, Robert J C, Jackie Rodger, Angela M Craigie, Treweek, S, Daly, Fergus, Stead, Martine, Annie S Anderson, Steele, R J, Anderson, A S, Kirk, A, Caswell, Stephen, Ludbrook, Anne, Wardle, J., Anne Ludbrook, Caswell, S, Belch, JJF, Ludbrook, A, Jill JF Belch, Craigie, Angela M, Steele, Robert J. C., Fergus Daly, Alison Kirk, Treweek, S., Joyce Thompson, Anderson, Annie S.; id_orcid, Craigie, Angela M.; id_orcid, Belch, Jill J. F.; id_orcid, Shaun Treweek, Craigie, AM, Belch, Jill, Craigie, A, Kirk, Alison, Jane Wardle, Wardle, Jane, Martine Stead, Stephen Caswell, Belch, J, Paterson, C, Anderson, AS, Anderson, Annie S, Treweek, Shaun, Stead, M, Paterson, Caron, Rodger, Jackie, Caron Paterson, Rodger, J, Thompson, J, Robert JC Steele, Steele, Robert, Thompson, Joyce, Craigie, Angela, Wardle, J, Daly, F, Anderson Annie S, Craigie Angela M, Stead Martine, Wardle Jane, Treweek Shaun, Thompson Joyce, Rodger Jackie, Daly Fergus, Steele Robert JC, Paterson Caron, Kirk Alison, Ludbrook Anne, Belch Jill JF, Caswell Stephen   +69 more
core   +2 more sources

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source