Results 81 to 90 of about 272,839 (312)

Oral antibiotic prophylaxis induces changes in the microbiology of surgical site infection after colorectal surgery. A matched comparative study [PDF]

Aim: Oral antibiotic prophylaxis (OAP) lowers rates of surgical site infection (SSI) and may aid anastomotic healing in colorectal surgery. The aim of this study was to analyse the understudied impact of OAP on SSI microbiology after colorectal surgery ...
Parés MD, PhD, EBSQ-Coloproctology, FACS, David, Juvany, Montserrat, Limón, Enrique, Pascual Damieta, Marta, Badia, Josep M, VINCat Colorectal Surveillance Team, Pujol Rojo, Miquel, Gomila Grange, Aina, Juvany, Montse, Gomila-Grange, Aina, PASCUAL, MARTA, Pujol, Miquel, Vázquez, Ana, Almendral, Alexander, Limón, Enric, Vázquez Fariñas, Ana, Flores-Yelamos, Miriam, Badia, Josep M., Parés, David, Gomila, Aina   +19 more
core   +1 more source

Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population [PDF]

, 2006
Background Bowel cancer is common and is a major cause of death. Meta-analysis of randomised controlled trials estimates that screening for colorectal cancer using faecal occult blood (FOB) test reduces mortality from colorectal cancer by 16%.
Redman, VD, Michael JO Wakelam, Colbourne, L, Janet A Dunn, Val D Redman, Lynne Colbourne, Dunn, Janet, Martin, A, Martin Ashley, Wilson, S, Wakelam, Michael, Ismail, T, Hobbs Richard FD, Wakelam, Michael J.O., Sue Wilson, Hobbs, RFD, Martin, Ashley, Wilson, Sue, Dr, Redman, Valerie, Colbourne Lynne, Wakelam, MJ, Redman, Val. D., Colbourne, Lynne, Ryan, Angela V., Wilson Sue, Angela V Ryan, Ryan, AV, Tariq Ismail, Fiona Patrick, Ashley Martin, Richard FD Hobbs, Ryan Angela V, Patrick, Fiona, Patrick, F, Ismail, Tariq, Ismail Tariq, Dunn, Janet A., Wilson, Sue, Redman Val D, Ryan, Angela, Dunn Janet A, Wakelam, MJO, Hobbs, RF, Dunn, JA, Hobbs, Richard F. D., Patrick Fiona, Wakelam Michael JO   +46 more
core   +1 more source

Impact and evolution of minimal invasive surgery in a centralized colorectal service: trends, safety and oncological outcomes across 15 years

World Journal of Surgical Oncology
Aim Specialization with subsequent evolving minimally invasive surgery (MIS) has been increasingly adopted in colorectal cancer care. This study aims to evaluate the impact of centralization and team specialization on oncologic quality and patient safety
Ali Toffaha, Mahmood Al-Dhaheri, Sherif Ahmed, Ayman Ahmed, Ibrahim Amer, Mahwish khawar, Ammar Aleter, Ejaz Latif, Hamza A. Abdul-Hafez, Salwa Ahmed, Mohammed Yousif, Noof Al Naimi, Mohamed A. Kurer, Amjad Parvaiz, Mohamed Abunada   +14 more
doaj   +1 more source

Hybrid Continuum Robot Designs and Architectures for Healthcare Applications

Advanced Robotics Research, EarlyView.
Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir, Muhammad A. Khalid, Manish Chauhan, Pietro Valdastri, James H. Chandler   +4 more
wiley   +1 more source

Establishment and validation of a novel nomogram incorporating clinicopathological parameters into the TNM staging system to predict prognosis for stage II colorectal cancer

Cancer Cell International, 2020
Background Survival outcomes are significantly different in stage II colorectal cancer (CRC) patients with diverse clinicopathological features. The objective of this study is to establish a credible prognostic nomogram incorporating easily obtained ...
Shaobo Mo, Zheng Zhou, Yaqi Li, Xiang Hu, Xiaoji Ma, Long Zhang, Sanjun Cai, Junjie Peng   +7 more
doaj   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Colorectal cancer: a comparative study of models of health care delivery in two adjacent trusts in South Wales [PDF]

, 2012
Introduction Survival in colorectal cancer patients is dependant on the stage of the cancer at diagnosis. Referral via an appropriate pathway to a specialist service is vital to the early detection of colorectal cancer but there is neither a standard ...
Shah, Parin Rajendra
core   +1 more source

Stromal‐Derived IL‐8 Promotes M2 Macrophage Polarization via the RhoA/MRTF‐A/SRF Transcriptional Axis to Impair CD8+ T Cell Cytotoxicity in Lung Cancer

Advanced Science, EarlyView.
In the recondite pulmonary neoplastic milieu, DESMIN+ cancer‐associated fibroblasts function as the paramount stromal source of IL‐8, precipitating a deleterious immunological metamorphosis by engaging CXCR2 receptors on the myeloid lineage. This paracrine stimulus triggers a mechanotransduction cascade characterized by RhoA‐dependent actin ...
Xuyu Gu, Qiyu Fang, Jia Yu, Ting Yu, Huashan Shi, Kaiqi Jin, Lei Jiang, Wentian Zhang   +7 more
wiley   +1 more source

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

Advanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang, Mengyu Zhang, Weipeng Gong, Jiaxuan Wu, Junping Zhang, Wenxiu Zhang, Yue Liu, Kui Wang, Canhua Huang, Jun Zhou, Sijin Wu, Yan Li, Tianliang Li   +12 more
wiley   +1 more source

Post-surgical morbidity in early versus late closure of defunctioning ileostomy after rectal cancer surgery: A systematic review and meta-analysis of randomised controlled trials

BMC Gastroenterology
Background A defunctioning ileostomy is frequently created to avert the implications of a colo-rectal anastomotic dehiscence in rectal cancer surgery. The timing of closure of the ileostomy remains debatable as it is believed that early closure (EC) may ...
Dedrick Kok Hong Chan, Jerrald Lau, Jarrod Kah-Hwee Tan, Bryan Jun Liang Buan, Kai-Yin Lee, Norman Sihan Lin, Ian Jse-Wei Tan, Jing-Yu Ng, Bettina Lieske, Wai-Kit Cheong, Ker-Kan Tan   +10 more
doaj   +1 more source