Results 111 to 120 of about 3,282,422 (392)

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Post-surgical morbidity in early versus late closure of defunctioning ileostomy after rectal cancer surgery: A systematic review and meta-analysis of randomised controlled trials

BMC Gastroenterology
Background A defunctioning ileostomy is frequently created to avert the implications of a colo-rectal anastomotic dehiscence in rectal cancer surgery. The timing of closure of the ileostomy remains debatable as it is believed that early closure (EC) may ...
Dedrick Kok Hong Chan, Jerrald Lau, Jarrod Kah-Hwee Tan, Bryan Jun Liang Buan, Kai-Yin Lee, Norman Sihan Lin, Ian Jse-Wei Tan, Jing-Yu Ng, Bettina Lieske, Wai-Kit Cheong, Ker-Kan Tan   +10 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Case report: Coexistence of rectal signet ring cell carcinoma with neuroendocrine components

BMC Geriatrics
Background Signet ring cell carcinoma is a rare histological type among the various forms of colorectal cancers. Even rare is when it coexisted with neuroendocrine components in one tumor.
Ling Xu, Zhefeng He, Chao Fu, Yiyang Wu, Anwei Wu, Guojiang Tian, Jianfei Huang, Xibo Liu, Qi Wang   +8 more
doaj   +1 more source

Characteristics and outcomes of colorectal cancer surgery by age in a tertiary center in Korea: a retrospective review [PDF]

, 2021
Tae‐Hoon Lee, Jeong Min Choo, Jeong Sub Kim, Seon Hui Shin, Ji-Seon Kim, Se Jin Baek, Jung‐Myun Kwak, Jin Kim, Seon Hahn Kim   +8 more
openalex   +1 more source

Enhanced recovery after surgery in emergency colorectal surgery: Review of literature and current practices

World Journal of Gastrointestinal Surgery, 2019
Enhanced recovery after surgery (ERAS), a multidisciplinary program designed to minimize stress response to surgery and promote the recovery of organ function, has become a standard of perioperative care for elective colorectal surgery.
V. Lohsiriwat, Romyen Jitmungngan
semanticscholar   +1 more source

Mandatory multidisciplinary approach for the evaluation of the lymph node status in rectal cancer [PDF]

, 2018
Colorectal cancer is the third most frequently reported malignancy and also the third leading cancer-related cause of death worldwide. Lymph node evaluation, both preoperatively and postoperatively, represents an important aspect of the diagnosis and ...
Ciorbagiu, Mihai C., Diaconescu, Marian, Mirea, Cecil S., Moraru, Emil, Obleaga, Cosmin V., Vilcea, Ionica D.   +5 more
core   +4 more sources

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang, Lu Lu, Hui Gao, Qi Zhang, Jing Xiao, Josemir W. Sander, Weixi Xiong, Dong Zhou   +7 more
wiley   +1 more source

Postoperative outcomes after prehabilitation for colorectal cancer patients undergoing surgery: a systematic review and meta-analysis of randomized and nonrandomized studies [PDF]

Annals of Coloproctology
Purpose Prehabilitation (PH) is purported to improve patients’ preoperative functional status. This systematic review and meta-analysis sought to compare short-term postoperative outcomes between patients who underwent a protocolized PH program and the ...
Ian Jun Yan Wee, Isaac Seow-En, Aik Yong Chok, Eileen Sim, Chee Hoe Koo, Wenjie Lin, Chang Meihuan, Emile Kwong-Wei Tan   +7 more
doaj   +1 more source

Prognostic impact of preoperatively elevated and postoperatively normalized carcinoembryonic antigen levels following curative resection of stage I‐III rectal cancer

Cancer Medicine, 2020
Background Preoperative and early postoperative serum carcinoembryonic antigen (CEA) levels are known prognostic factors in rectal cancer. Recently, a large‐scale study on colon cancer revealed that “preoperatively elevated and postoperatively normalized
Yuya Nakamura, Dai Shida, Taro Tanabe, Yasuyuki Takamizawa, Jun Imaizumi, Yuka Ahiko, Ryohei Sakamoto, Konosuke Moritani, Shunsuke Tsukamoto, Yukihide Kanemitsu   +9 more
doaj   +1 more source