Results 131 to 140 of about 3,606,891 (358)

The effects of oxaliplatin-based adjuvant chemotherapy in high-risk stage II colon cancer with mismatch repair-deficient: a retrospective study

BMC Cancer
Background For high-risk stageIImismatch repair deficient (dMMR) colon cancers, the benefit of adjuvant chemotherapy remains debatable. The principal aim of this study was to evaluate the prognostic value of high-risk factors and the effect of ...
Leen Liao, Jinghua Tang, Zhigang Hong, Wu Jiang, Yuan Li, Lingheng Kong, Kai Han, Zhenlin Hou, Chenzhi Zhang, Chi Zhou, Linjie Zhang, Qiaoqi Sui, Binyi Xiao, Weijian Mei, Jiehai Yu, Wanjun Yang, Zhizhong Pan, Pei-Rong Ding   +17 more
doaj   +1 more source

Postoperative outcomes after prehabilitation for colorectal cancer patients undergoing surgery: a systematic review and meta-analysis of randomized and nonrandomized studies [PDF]

Annals of Coloproctology
Purpose Prehabilitation (PH) is purported to improve patients’ preoperative functional status. This systematic review and meta-analysis sought to compare short-term postoperative outcomes between patients who underwent a protocolized PH program and the ...
Ian Jun Yan Wee, Isaac Seow-En, Aik Yong Chok, Eileen Sim, Chee Hoe Koo, Wenjie Lin, Chang Meihuan, Emile Kwong-Wei Tan   +7 more
doaj   +1 more source

Patients' inability to perform a preoperative cardiopulmonary exercise test or demonstrate an anaerobic threshold is associated with inferior outcomes after major colorectal surgery. [PDF]

, 2013
BACKGROUND: Surgical patients with poor functional capacity, determined by oxygen consumption at anaerobic threshold (AT) during cardiopulmonary exercise testing (CPET), experience longer hospital stays and worse short- and medium-term survival. However,
Buck, C.P. Challand, C.W. Lai, Carli, Carlisle, Challand, Chase, Copeland, G Minto, J.R. Sneyd, K.B. Hosie, Mayo, Older, Older, Pearse, R.A. Struthers, S Creanor, Shoemaker, Shoemaker, Swart, Tekkis, Visser, Wilson   +22 more
core   +3 more sources

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Risk and Management of Bowel Obstruction in Colorectal Cancer Patients Undergoing Immunotherapy: A Cross-Sectional Multicenter Study

ImmunoTargets and Therapy
Zhi-Gang Hong,1,2,* Binyi Xiao,1,2,* Muxu Zheng,1,2,* Wanjun Yang,1,2,* Liangjun Zhu,3 Guodong Liang,4 Yuhao Luo,5 Jinghua Tang,1,2 Weijian Mei,1,2 Jie-Hai Yu,1,2 Zhenlin Hou,1,2 Xiaojun Wu,1,2 Peirong Ding,1,2 Wu Jiang1,2
Hong ZG, Xiao B, Zheng M, Yang W, Zhu L, Liang G, Luo Y, Tang J, Mei W, Yu JH, Hou Z, Wu X, Ding P, Jiang W   +13 more
doaj  

A retrospective cohort study of the influence of lifestyle factors on survival of patients undergoing surgery for colorectal cancer. [PDF]

, 2017
Aim: Several modifiable and non-modifiable health related behaviours are associated with the incidence of Colorectal Cancer (CRC), but there is little research on their association with survival.
Anderson, Boyle, Campbell, Courneya, Courneya, Dignam, Haggar, Haydon, Holmes, Hubbard, Kuiper, Manceau, Martinez, Meyerhardt, Meyerhardt, Morrison, Oliphant, Shafique, Van Blarigan, Vartiainen, Vrieling, World Cancer Research Fund/American Institute for Cancer Research   +21 more
core   +1 more source

Enhanced recovery after surgery in emergency colorectal surgery: Review of literature and current practices

World Journal of Gastrointestinal Surgery, 2019
Enhanced recovery after surgery (ERAS), a multidisciplinary program designed to minimize stress response to surgery and promote the recovery of organ function, has become a standard of perioperative care for elective colorectal surgery.
V. Lohsiriwat, Romyen Jitmungngan
semanticscholar   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Preoperative Prognostic Nutritional Index Predicts Postoperative Outcomes in Colorectal Cancer: A Propensity Score-Matched Cohort Study

Cancer Management and Research
Chew-Teng Kor,1– 3 Tsung-Jung Tsai,4 Tsung Chuang,4 Jui-Shen Chang,4 Wei-Huan Chen,4 Chang-Wei Chen,4 Yen-Hang Wu,4 Yu-Shih Liu,4 Xuan-Yuan Huang,4 Yu-Yao Chang4– 6 1Graduate Institute of Clinical Medicine, College of Medicine, National Chung Hsing ...
Kor CT, Tsai TJ, Chuang T, Chang JS, Chen WH, Chen CW, Wu YH, Liu YS, Huang XY, Chang YY   +9 more
doaj  

Systemic inflammation, nutritional status and survival in patients with cancer [PDF]

, 2009
Systemic inflammation, nutritional status and survival in patients with ...
Al Murri, Brown, Cho, Crumley, Crumley, Crumley, Fearon, Forrest, Forrest, Gabay, Glen, Gomez, Gridelli, Halazun, Hara, Hilmy, Ishizuka, Jamieson, Karakiewicz, Kerem, Kobayashi, Krzystek-Korpacka, Leitch, Malik, Marsik, McMillan, McMillan, Morley, Ramsey, Read, Sharma, Sharma, Walsh, Yamanaka   +33 more
core   +1 more source