Results 171 to 180 of about 3,606,891 (358)

Mapping the landscape of locally advanced colon cancer research: a 30-year bibliometric perspective

Discover Oncology
Our study aimed to perform a comprehensive bibliometric analysis to investigate the evolution of research in locally advanced colon cancer (LACC) over the past 30 years. This study examined 206 articles from the Science Citation Index Expanded within the
Yanwu Sun, Zhiping Chen, Zihan Tang, Zhenyu Xu, Hongfeng Pan, Pan Chi, Ying Huang   +6 more
doaj   +1 more source

Laparoscopic Colorectal Surgery [PDF]

Gastroenterology, 2000
openaire   +2 more sources

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source

Liquid biopsy in cancer drug resistance: real-time monitoring, mechanistic insights, and translational applications

Frontiers in Immunology
Liquid biopsy provides a non-invasive approach for cancer detection. It examines tumor-associated components in blood and other body fluids, including circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and extracellular vesicles (EVs ...
Yiyang Li, Zixuan Liu, Benliang Yuan, Tianshuai Zhang, Xiaoming Zhu, Leqi Zhou, Wei Zhang, Guanyu Yu   +7 more
doaj   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

A Modular and Programmable Cas13d Platform for RNA Single Nucleotide Variant Detection

Advanced Science, EarlyView.
A scenario‐guided Cas13d platform enables configurable single nucleotide variant ribonucleic acid diagnostics through rule‐based guide design and ribonucleic acid binding domain engineering, supporting amplification‐free ultrasensitive detection and amplification‐coupled robust detection for accurate mutation classification in clinical tumor specimens.
Zeyu Wang, Jiahao Li, Zhuying Yue, Beixuan He, Wenhua Zhang, Zhen Fang, Qing Xia, Yingbin Liu, Yanjing Li   +8 more
wiley   +1 more source

Proficient surgeons enhance conversion rates and sphincter preservation in robotic rectal cancer surgery with comparable long-term outcomes: a comparative study with laparoscopy in a large-volume center in China

BMC Cancer
Background Despite theoretical advantages, skepticism persists about robotic rectal cancer surgery due to the lack of evidence of benefit. This study aims to compare oncological and functional results of robotic-assisted surgery to laparoscopy, focusing ...
Xiaojie Wang, Yangyang Wang, Zhifen Chen, Zhifang Zheng, Shenghui Huang, Yanwu Sun, Ying Huang, Pan Chi   +7 more
doaj   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Secondary Perianal Paget’s Disease Originating From Adenocarcinoma of the Anorectal Junction: A Case Report

Clinical, Cosmetic and Investigational Dermatology
Jun He,1,* Rong-Chao He,2,* Jian-Zhong Peng,3 Hou-Dong Wang,1 Tao Wang,3 Si-Jia Lu,4 Xiu-Feng Zhang,1 Zhong Shen1 1Department of Colorectal Surgery, Hangzhou Third People’s Hospital, Hangzhou, Zhejiang, People’s Republic of China; 2School
He J, He RC, Peng JZ, Wang HD, Wang T, Lu SJ, Zhang XF, Shen Z   +7 more
doaj  

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source