Results 71 to 80 of about 64,693 (310)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Evaluation of the Antibacterial Activity of Annatto Dye on Some Pathogenic Bacteria

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives:Today, disadvantages of antibiotics and synthetic preservatives have been identified, and researchers are seeking natural and safe alternatives.
Mahmoud Yolmeh   +3 more
doaj  

Reactive Blue 203 dye Removal Using Biosorbent: A Study of Isotherms, Kinetics, and Thermodynamics [PDF]

open access: yesAvicenna Journal of Environmental Health Engineering, 2018
Nowadays, due to increasing usage of dye in various industries and its destructive effects on health and environment, it is necessary to remove dyes from industrial wastes.
Marzieh Bagheri   +2 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Determination of Synthetic Colors in Some Locally Available Foods of Kashan City, Iran

open access: yesInternational Archives of Health Sciences, 2016
Aims: The synthetic colors are preferred by the food industry because of the variety of shades, intensity, uniformity, excellent solubility and stability.
Sharafati Chaleshtori R.* PhD,   +1 more
doaj  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Population stability: regulating size in the presence of an adversary

open access: yes, 2018
We introduce a new coordination problem in distributed computing that we call the population stability problem. A system of agents each with limited memory and communication, as well as the ability to replicate and self-destruct, is subjected to attacks ...
Aspnes James   +7 more
core   +1 more source

Biodecolourization of Azo Dye under Extreme Environmental Conditions via Klebsiella quasipneumoniae GT7: Mechanism and Efficiency

open access: yesJournal of Environmental Health and Sustainable Development, 2022
Introduction: Biodegradation of azo dyes under harsh environmental conditions has been of great interest for the treatment of colored effluents. The present study aims to evaluate Klebsiella quasipneumoniae GT7 for degrading azo dye Carmoisine under ...
Maryam Karimzadeh   +3 more
doaj  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

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