Results 121 to 130 of about 651,271 (313)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Towards Colour Imaging with the Image Ranger

open access: yes, 2006
Many of the colour images captured by different types of digital camera do not provide quality colour image according to human visual perception. In this study we explore technique for colour correction of the colour images from the Waikato Image Ranger.
Muttayane, Anandajothi
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Additive colour system

open access: yes, 2006
This is a basic introduction to colour theory : additive colour. It is suitable for Art and Design, the Print Industry, Beauty Therapy and Multimedia students.
Lewis Jones
core  

Poly(amino acid) Synthesis from 2,5‐Diketopiperazines for Acid‐Actuated Drug Release

open access: yesMacromolecular Materials and Engineering
Poly(amino acids) have enormous potential value as biomaterials owing to their inherent biocompatibility, chemical functionality, and biodegradability. However, current commercial poly(amino acid) use is somewhat limited due to production protocols that ...
Patrick A. Wall   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Colour concept generator: a computer tool to propose colour concepts for products.

open access: yes
This thesis documents research undertaken into the design and evaluation of a computer tool (Colour Concept Generator) to produce colour schemes for products from verbal descriptors depicting a required aesthetic image or style.
Eves, Bob
core  

Colours technology for an innovative Reclamation Architecture

open access: yes, 2018
Within the broad area of landscape design and enhancement there is a growing interest in the valorisation of spaces where the reclamation architectures are built.
Alessandro Premier, Gasparini Katia
core  

Red socks and purple rain: the political uses of colour in late apartheid South Africa

open access: yes, 2011
This is a post-print of the published version of a SAGE Journal article available on: http://dx.doi.org/10.1177/1470357211398437.This article explores the extent to which colour functions as an independent mode in a particular context and explores the ...
Stacey Stent   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy