Bioactive Lipophilic Antioxidants (Carotenoids, Tocols, Retinol, and Coenzyme Q10) in Human and Animal Tissues: Development and Validation of a Rapid Extraction and Chromatographic Method for Nutrition and Health Studies [PDF]
AntioxidantsA rapid and robust analytical method was validated for the simultaneous extraction and quantification of carotenoids and other lipophilic antioxidants (tocopherols, tocotrienols, retinol and coenzyme Q10) in human and animal tissues using a tandem RRLC ...
Ana M. Benítez-González +4 more
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Preliminary Data on the Safety of Phytoene- and Phytofluene-Rich Products for Human Use including Topical Application [PDF]
Journal of Toxicology, 2018 The colorless carotenoids phytoene and phytofluene are comparatively understudied compounds found in common foods (e.g., tomatoes) and in human plasma, internal tissues, and skin. Being naturally present in common foods, their intake at dietary levels is
Fabien Havas +3 more
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Isolation of Carrot Chromoplasts and Assessment of Their Carotenoid Content and Bioaccessibility [PDF]
MoleculesThe bioaccessibility (fraction of compounds released from the food matrix and available for absorption) and carotenoid content of carrot chromoplasts obtained through high-speed centrifugation using sucrose gradients were assessed.
Ana M. Benítez-González +5 more
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Dietary carotenoids and breast cancer risk: evidence from a large population-based incident case-control study [PDF]
Nutrition & MetabolismBackground Although mechanistic studies suggest protective roles for carotenoids against breast cancer (BC), human studies yield inconsistent findings. Few have comprehensively evaluated dietary intake of individual and grouped carotenoids in relation to
Bahar Darouei +6 more
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Metabolically engineered plant cell cultures as biofactories for the production of high-value carotenoids astaxanthin and canthaxanthin [PDF]
Scientific ReportsAstaxanthin and canthaxanthin are high-value carotenoids with growing demand due to their antioxidant properties and applications in food, cosmetic, and pharmaceutical sectors. However, natural sources are limited and current production methods are often
Bárbara A. Rebelo +2 more
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Hot Spots of Phytoene Desaturase from Rhodobacter sphaeroides Influencing the Desaturation of Phytoene [PDF]
Catalysts, 2021 Phytoene desaturase (CrtI, E.C. 1.3.99.31) shows variable desaturation activity, thereby introducing different numbers of conjugated double bonds (CDB) into the substrate phytoene. In particular, Rhodobacter sphaeroides CrtI is known to introduce additional 6 CDBs into the phytoene with 3 CDBs, generating neurosporene with 9 CDBs.
Bo Hyun Choi +2 more
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Mitosis Inhibitors Induce Massive Accumulation of Phytoene in the Microalga Dunaliella salina
Marine Drugs, 2021 Phytoene is a colourless natural carotenoid that absorbs UV light and provides antioxidant and anti-inflammatory activities as well as protection against photodamage.
Yanan Xu, Patricia J. Harvey
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Marine Drugs, 2022 Chlorpropham is a carbamate herbicide that inhibits cell division and has been widely used as a potato sprout suppressant. Recently we showed that the microalga Dunaliella salina treated with chlorpropham massively accumulated the colourless carotenoids ...
Laura Mazzucchi +2 more
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Stereoisomers of Colourless Carotenoids from the Marine Microalga Dunaliella salina
Molecules, 2020 Carotenoids comprise a diverse range of naturally occurring stereoisomers, which differ in their physico-chemical properties. Their biosynthesis begins with phytoene, which is a rarity among carotenoids because it is colourless.
Laura Mazzucchi +2 more
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Safety of yellow/orange tomato extract as a novel food pursuant to Regulation (EU) 2015/2283
EFSA Journal, 2023 Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on yellow/orange tomato extract used as a novel food (NF) pursuant to Regulation (EU) 2283/2015.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) +29 more
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