Bioactive Lipophilic Antioxidants (Carotenoids, Tocols, Retinol, and Coenzyme Q10) in Human and Animal Tissues: Development and Validation of a Rapid Extraction and Chromatographic Method for Nutrition and Health Studies [PDF]
AntioxidantsA rapid and robust analytical method was validated for the simultaneous extraction and quantification of carotenoids and other lipophilic antioxidants (tocopherols, tocotrienols, retinol and coenzyme Q10) in human and animal tissues using a tandem RRLC ...
Ana M. Benítez-González +4 more
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Diversification of tobacco phytoene-synthase-encoding genes coordinates carotenoid flux, strigolactone biosynthesis, and cold responses [PDF]
Frontiers in Plant SciencePhytoene synthase plays important roles in the development, metabolism, and various stress tolerance in plants. In the current study, a total of five tobacco phytoene synthase members were identified and systemically analyzed from the latest genome ...
Xiaoxu Li +18 more
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Protective effects of colorless carotenoid precursors against UV-induced lipid oxidation in liposomes compared to lycopene [PDF]
Scientific ReportsConsuming tomato-extracts can reduce the risk of developing chronic diseases. As lycopene supplementation alone had a weaker impact, the protective effect may be influenced by the colorless carotenoids phytoene and phytofluene.
Anna Heidrich, Volker Böhm
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Dietary carotenoids and breast cancer risk: evidence from a large population-based incident case-control study [PDF]
Nutrition & MetabolismBackground Although mechanistic studies suggest protective roles for carotenoids against breast cancer (BC), human studies yield inconsistent findings. Few have comprehensively evaluated dietary intake of individual and grouped carotenoids in relation to
Bahar Darouei +6 more
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Marine Drugs, 2019 Carotenoids are lipophilic pigments found in plants and algae, as well as some bacteria, archaea, and fungi that serve two functions—(1) as light harvesting molecules—primary carotenoids, and (2) as antioxidants, acting against reactive ...
Kelly Laje +5 more
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Aquatic Biology, 2020 Phytoene and astaxanthin are 2 important carotenoids in the green alga Haematococcus pluvialis. Under environmental stress, the synthesis of phytoene in H.
Cong, X +11 more
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Frontiers in Nutrition, 2022 5-Aminolevulinic acid (ALA) plays a vital role in promoting plant growth, enhancing stress resistance, and improving fruit yield and quality. In the present study, tomato fruits were harvested at mature green stage and sprayed with 200 mg L–1 ALA on ...
Junwen Wang +10 more
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The stereospecific biosynthesis of phytoene and polyunsaturated carotenes [PDF]
Biochemical Journal, 1967 1. The incorporation of [2-(14)C,(5R)-5-(3)H(1)]mevalonic acid and [2-(14)C,5-(3)H(2)]-mevalonic acid into phytoene, phytofluene, zeta-carotene, neurosporene, alpha-, beta-, gamma- and delta-carotene and lycopene by slices of fruit from two tomato mutants (delta and tangerine) and into alpha- and beta-carotene by bean leaves has been studied. 2. In the
R J, Williams +3 more
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Stereochemistry of phytoene biosynthesis by isolated chloroplasts [PDF]
Biochemical Journal, 1969 The incorporation of [2−14C,(5R)-5−3H1]MVA* and [2−14C,5−3H2]MVA into geranylgeraniol and phytoene by a preparation of ‘non-aqueous’ bean leaf chloroplasts has been studied. In the formation of phytoene from two molecules of geranylgeranyl pyrophosphate, the loss of hydrogen is stereospecific, the hydrogen atom lost from C-1 of each molecule of ...
M J, Buggy, G, Britton, T W, Goodwin
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On the structure and function of the phytoene desaturase CRTI from Pantoea ananatis, a membrane-peripheral and FAD-dependent oxidase/isomerase. [PDF]
PLoS ONE, 2012 CRTI-type phytoene desaturases prevailing in bacteria and fungi can form lycopene directly from phytoene while plants employ two distinct desaturases and two cis-tans isomerases for the same purpose. This property renders CRTI a valuable gene to engineer
Patrick Schaub +9 more
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