Results 101 to 110 of about 1,099,712 (300)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Kinetics of colour change in roasted ground coffee during secondary shelf-life [PDF]

Journal on Processing and Energy in Agriculture, 2015
Coffee represents an interesting foodstuff for secondary shelf life   modelling, since it is know that almost immediately after its exposure to   environmental influences, aroma and colour degradation reactions occur.
Jurinjak-Tušek Ana, Benković Maja, Bauman Ingrid   +2 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Detection of a spiral lens galaxy and optical variability in the gravitational lens system B1600+434 [PDF]

, 1996
The gravitationally lensed quasar B1600+434 (z=1.61, mV=21.6) has been observed at the 2.56m Nordic Optical Telescope (NOT). In this Letter we report the discovery of an edge-on late-type galaxy located between the two lensed components (separation 1 ...
Hjorth, J., Jaunsen, A. O.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Scorpionfish adjust skin pattern contrast on different backgrounds

Ecology and Evolution
The two scorpionfish species Scorpaena maderensis and S. porcus are well camouflaged ambush predators that rapidly change body colouration to adjust to background colour in less than 1 min.
Leonie John, Matteo Santon, Nico K. Michiels   +2 more
doaj   +1 more source

Colour Change Kinetics of the Inner and Outer Surface of Brussels Sprouts during Microwave Drying Process

Journal of Agricultural Sciences, 2018
The effect of microwave output powers on colour change kinetics of the inner and outer surface of brussels sprouts was investigated during microwave drying process.
Emine Nakilcioğlu-taş, Semih Ötleş
doaj   +1 more source

The Comparison Analysis of Land Cover Change Based on Vegetation Index and Multispectral Classification (Case Study Leihitu Peninsula Ambon City District) [PDF]

, 2015
The study utilized Landsat-7 ETM+ 2001and Landsat TM5 2009 based on Normalized Differences Vegetation Index (NDVI) and 457 colour composite at the study area located in Leihitu Peninsula, Ambon City District, Ambon Island, Moluccas Province.
Baiquni, M. (M), Danoedoro, P. (P), Khakhim, N. (N), Siahaya, W. A. (W)   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source