Results 31 to 40 of about 451,802 (301)

A Hybrid Column Generation and Clustering Approach to the School Bus Routing Problem with Time Windows

Un Aproximación Híbrida de Generación de Columnas y Agrupación para Resolver el Problema de Ruteo de Buses Escolares con Ventanas deTiempo

open access: yesIngeniería, 2015
This paper attempts to solve the School Bus Routing Problem with Time Windows that consists of finding the best set of routes to pick up students distributed geographically with constraints as capacity, time windows and maximum travel time. We formulated
Eduyn Ramiro Lopez Santana   +1 more
doaj   +1 more source

A Three-Stage Optimization Method for Assembly Line Balancing Problem

open access: yesIEEE Access, 2020
Considering the characteristics of multimodels production pattern on assembly line, the assembly line balancing problem which is non-deterministic polynomial hard becomes more challenging to complete. In this article, we propose a reformulation of simple
Qidong Yin, Xiaochuan Luo
doaj   +1 more source

Pedestrian evacuation planning: Unveiling evacuation routes via column generation

open access: yesEURO Journal on Transportation and Logistics, 2022
Evacuation drills are critical to evaluate emergency preparedness and infrastructure capacity. Before conducting drills, it is necessary to design the evacuation routes that people are likely to follow in a real evacuation.
Nicolás Cabrera   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A column generation approach to the airline crew pairing problem to minimize the total person-days

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2016
In this paper, we consider the crew pairing problem in airline scheduling that calls for assigning crew members in order to cover all flights with the minimum total person-days under the constraints that the schedule of each crew member does not violate ...
Wei WU   +5 more
doaj   +1 more source

A Column Generation-Based Lower Bound for the Minimum Sum Coloring Problem

open access: yesIEEE Access, 2020
The objective of this paper is to derive a tight and efficient lower bound for the minimum sum coloring problem. This NP-hard problem is a variant of the classical graph coloring problem where the objective is to minimize the sum of the colors.
Mehdi Mrad   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Constrained Clustering Using Column Generation [PDF]

open access: yes, 2014
In recent years, it has been realized that many problems in data mining can be seen as pure optimisation problems. In this work, we investigate the problem of constraint-based clustering from an optimisation point of view. The use of constraints in clustering is a recent development and allows to encode prior beliefs about desirable clusters.
Babaki, Behrouz   +2 more
openaire   +3 more sources

Region-Based Relaxed Multiple Kernel Collaborative Representation for Hyperspectral Image Classification

open access: yesIEEE Access, 2017
This paper presents a region-based relaxed multiple kernel collaborative representation method for the spatial-spectral classification of hyperspectral images. The proposed method consists of three steps.
Jianjun Liu   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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