Results 41 to 50 of about 3,531,799 (287)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
A column generation approach to the airline crew pairing problem to minimize the total person-days
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2016 In this paper, we consider the crew pairing problem in airline scheduling that calls for assigning crew members in order to cover all flights with the minimum total person-days under the constraints that the schedule of each crew member does not violate ...
Wei WU +5 more
doaj +1 more source
A Column Generation-Based Lower Bound for the Minimum Sum Coloring Problem
IEEE Access, 2020 The objective of this paper is to derive a tight and efficient lower bound for the minimum sum coloring problem. This NP-hard problem is a variant of the classical graph coloring problem where the objective is to minimize the sum of the colors.
Mehdi Mrad +3 more
doaj +1 more source
Pedestrian evacuation planning: Unveiling evacuation routes via column generation
EURO Journal on Transportation and Logistics, 2022 Evacuation drills are critical to evaluate emergency preparedness and infrastructure capacity. Before conducting drills, it is necessary to design the evacuation routes that people are likely to follow in a real evacuation.
Nicolás Cabrera +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
IEEE Access, 2017 This paper presents a region-based relaxed multiple kernel collaborative representation method for the spatial-spectral classification of hyperspectral images. The proposed method consists of three steps.
Jianjun Liu +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Energy Efficient Resource Allocation in Cloud Computing Environments
IEEE Access, 2016 Power consumption is one of the major concerns for the cloud providers. The issue of disorganized power consumption can be categorized into two main groups: one caused by server operations and one occurred during the network communications. In this paper,
Shahin Vakilinia +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source