Results 41 to 50 of about 451,802 (301)

A genetic column generation algorithm for sustainable spare part delivery: Application to the Sydney DropPoint Network [PDF]

, 2018
Modern-day logistics companies require increasingly shorter lead-times in order to cater for the increasing popularity of on-demand services. There is consequently an urgent need for fast scheduling algorithms to provide high quality, real-time ...
Shukla, N, Amirghasemi, Mehrdad, Mehrdad Amirghasemi, Nishikant Mishra, Belieres, S, Dunbar, M, Perez, P, Shukla, Nagesh, Mishra, Nishikant, Amirghasemi, M, Simon Belieres, Nagesh Shukla, Mishra, N, Perez, Pascal, Dunbar, Michelle, Michelle Dunbar, Pascal Perez, Belieres, Simon   +17 more
core   +1 more source

Energy Efficient Resource Allocation in Cloud Computing Environments

IEEE Access, 2016
Power consumption is one of the major concerns for the cloud providers. The issue of disorganized power consumption can be categorized into two main groups: one caused by server operations and one occurred during the network communications. In this paper,
Shahin Vakilinia, Behdad Heidarpour, Mohamed Cheriet   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

An Improved Column Generation Algorithm Based on Minimum-Norm Multipliers

Mathematics
Column generation is a fundamental technique for solving large-scale combinatorial optimization problems such as unit commitment and vehicle routing, yet its performance is often limited by dual oscillation.
Dingfang Su, Jie Tao, Jiaxu Huang, Erzhan Gao   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Learning assisted column generation for model predictive control based energy management in microgrids

Energy Reports, 2023
Model predictive control is an effective approach for microgrid energy management. However, the main downside of such method is its expensive online computational cost, which is not amenable to most practical microgrid implementations.
Yuchong Huo, Zaiyu Chen, Jing Bu, Minghui Yin   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Advances in interior point methods and column generation [PDF]

, 2013
In this thesis we study how to efficiently combine the column generation technique (CG) and interior point methods (IPMs) for solving the relaxation of a selection of integer programming problems.
Brevis, Pablo, González Brevis, Pablo
core  

Chvátal–Gomory Cuts Applied to the Nurse Rostering Problem

Systems
The nurse rostering problem (NRP) has attracted significant research interest in recent decades due to both its practical relevance and computational complexity.
Yuanyuan Fang, Wanzhe Hu, Li Luo
doaj   +1 more source