Results 61 to 70 of about 451,802 (301)

Optimizing Train Formation Problem With Car Flow Routing and Train Routing by Benders-and-Price Approach

open access: yesIEEE Access, 2019
As the core of the rail freight flow organization process, train formation problem (TFP) has attracted much attention. In Chinese practice, car flow routing, TFP, and train routing are usually optimized sequentially to reduce the complexity of ...
Zekang Lan   +3 more
doaj   +1 more source

A Coordinated Optimization of Rewarded Users and Employees in Relocating Station–Based Shared Electric Vehicles

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2022
To solve the mismatch between the supply and demand of shared electric vehicles (SEVs) caused by the uneven distribution of SEVs in space and time, an SEV relocating optimization model is designed based on a reward mechanism.
Yu Lan, Liu Jiaming, Sun Zhuo
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Column generation in the integral simplex method

open access: yesEuropean Journal of Operational Research, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Elina Rönnberg, Torbjörn Larsson
openaire   +4 more sources

Integrated Optimization of Bunker–Cargo Trade-Offs in Tramp Ship Routing and Scheduling

open access: yesApplied Sciences
This paper studies an integrated planning problem in tramp shipping operations, with a particular focus on the bunker–cargo trade-off in maritime logistics.
Lingrui Kong   +4 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A column generation algorithm for nonlinear programming [PDF]

open access: yesMathematical Programming, 1973
An algorithm using column generation and penalty function techniques is presented. A linear program with a uniformly bounded number of columns, similar to the restricted master in generalized programming, is used to reduce the number of constraints included in forming a penalty function.
openaire   +2 more sources

Gas hold-up and bubble diameters in a gassed oscillatory baffled column

open access: yes, 2001
In this paper attempts are made to address how bubble behaviour in a batch oscillatory ba'ed column (OBC) contributes to the overall measured enhancement in mass transfer.
Ni, X.   +6 more
core   +1 more source

Neural Column Generation for Capacitated Vehicle Routing

open access: yes, 2022
The dataset used in the experiments of the paper "Neural Column Generation for Capacitated Vehicle ...
Babaki, Behrouz   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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