Results 41 to 50 of about 1,530,542 (289)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Energy Efficient Resource Allocation in Cloud Computing Environments

IEEE Access, 2016
Power consumption is one of the major concerns for the cloud providers. The issue of disorganized power consumption can be categorized into two main groups: one caused by server operations and one occurred during the network communications. In this paper,
Shahin Vakilinia, Behdad Heidarpour, Mohamed Cheriet   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Learning assisted column generation for model predictive control based energy management in microgrids

Energy Reports, 2023
Model predictive control is an effective approach for microgrid energy management. However, the main downside of such method is its expensive online computational cost, which is not amenable to most practical microgrid implementations.
Yuchong Huo, Zaiyu Chen, Jing Bu, Minghui Yin   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Column-Generation in Integer Linear Programming [PDF]

RAIRO - Operations Research, 2003
This article presents an exact method for solving integer and binary linear programming problems based on the branch-and-price technique. The article begins with an overview of branch-and-price column generation techniques as applied to integer linear programs (LP), which is then followed by an overview of applications, e.g., the vehicle routing ...
Maculan, Nelson, de Mendonça Passini, Marcos, de Moura Brito, José André, Loiseau, Irene   +3 more
openaire   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Column Generation Technique for Solving Two-dimensional Cutting Stock Problems: Method of Stripe Approach [PDF]

, 2007
We consider two-dimensional cutting stock problems where single rectangular stocks have to be cut into some smaller rectangular so that the number of stocks needed to satisfy the demands is minimum.
Hadianti, R. (R), Novianingsih, K. (K), Uttunggadewa, S. (S)   +2 more
core  

Vortex Bubble Formation in Pair Plasmas [PDF]

, 2013
It is shown that delocalized vortex solitons in relativistic pair plasmas with small temperature asymmetries can be unstable for intermediate intensities of the background electromagnetic field.
Aleksić, B. N., Berezhiani, V. I., Mahajan, S. M., Shatashvili, N. L.   +3 more
core   +4 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source