Results 51 to 60 of about 835,149 (319)

Descripció codicològica del MS 658 de la Biblioteca de Catalunya. Liber fratris Alberti de ordine predicatorum De laude beatae Virginis [PDF]

open access: yes, 2016
Màster de Cultures Medievals. Assignatura Codicologia de la Facultat de Filologia de la Universitat de Barcelona. Curs: 2015-2016, Directora: Gemma Avenzoa.Estudi codicològic del manuscrit 658: Liber fratris Alberti de ordine predicatorum De laude beatae
Blanco Escoda, Xavier
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Local Perceptions of Ecosystem Services Across Multiple Ecosystem Types in Spain

open access: yesLand, 2020
Combining socio-cultural valuations of ecosystem services with ecological and monetary assessments is critical to informing decision making with an integrative and multi-pronged approach.
Marina García-Llorente   +13 more
doaj   +1 more source

El temple de Barcelona dedicat a l'emperador August [PDF]

open access: yes, 2013
En el tema d'avui, donarem una ullada al temple que la Barcelona antiga va dedicar a l'emperador August, en aquells temps quan la Colònia de Barcino era un assentament de les legions romanes, en la seva expansió de domini sobre les pobles ibèrics de la ...
Ballart Clos, Joan
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An Integrated Paleoenvironmental Reconstruction of the Early Pleistocene Hominin-Bearing Site of Dursunlu (Türkiye)

open access: yesDiversity
The fossiliferous Dursunlu Lignite Quarry (DLQ) is highlighted prominently in the archeological and paleontological literature because of the study of Pleistocene fauna and lithic artifacts, being considered the oldest Paleolithic site in Türkiye ...
Àngel H. Luján   +9 more
doaj   +1 more source

Phosphorus assay in column chromatography.

open access: yesJournal of Biological Chemistry, 1959
Malerials-30 per cent hydrogen peroxide (Baker and Adamson, phosphorus-free) and the ammonium molybdate, (NHJ6lMo7024.4Hz0, wereused. The Fiske and SubbaRow (I) reagent was prepared by adding 0.5 gm.
G. R. Bartlett
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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