Results 71 to 80 of about 2,566,141 (344)

Block CUR: Decomposing Matrices using Groups of Columns

open access: yes, 2018
A common problem in large-scale data analysis is to approximate a matrix using a combination of specifically sampled rows and columns, known as CUR decomposition.
C Boutsidis   +8 more
core   +1 more source

Design charts for channel shaped reinforced concrete short columns subjected to axial compressive load and uniaxial bending [PDF]

open access: yesEngineering and Technology Journal, 2009
Eight design charts are presented for reinforced concrete short C-columns subjected to axial compressive load plus uniaxial bending. For design these charts can be used for determining the required column dimensions and amount of steel, while for ...
Sarmad S. Abdul-Qader AL-Badri   +1 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Column Chromatography [PDF]

open access: yesCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractColumn chromatography is used extensively in nucleic acid chemistry to purify or characterize products from chemical reactions. This appendix focuses on separations using silica gel or alumina. The procedures described include loading the column, assembling the apparatus, separating compounds and collecting fractions, and optimizing ...
openaire   +3 more sources

Monotonic and Cyclic Seismic Analyses of Old-Type RC Columns with Short Lap Splices

open access: yesConstruction Materials
Reinforced concrete (RC) columns with short lap splices built in the early 1970s or before are known to have deficient seismic strength and ductility. These short lap splices are poorly confined and located right above the foundation level, where it is ...
Konstantinos G. Megalooikonomou
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Strain and correlation of self-organized Ge_(1-x)Mn_x nanocolumns embedded in Ge (001)

open access: yes, 2010
We report on the structural properties of Ge_(1-x)Mn_x layers grown by molecular beam epitaxy. In these layers, nanocolumns with a high Mn content are embedded in an almost-pure Ge matrix. We have used grazing-incidence X-ray scattering, atomic force and
Arras, E.   +10 more
core   +3 more sources

Nonlinear analysis of lightweight aggregate concrete columns

open access: yesBudownictwo i Architektura, 2020
The paper presents a numerical analysis of deformability and load-bearing capacity of lightweight aggregate concrete (LWAC) elements subjected to bending with axial force.
Ewelina Kołodziejczyk   +1 more
doaj   +1 more source

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