Results 91 to 100 of about 1,013,319 (286)

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

open access: yesAdvanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li   +13 more
wiley   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

Combat Sports

open access: yes
Kaia! Readers of this text will learn about women who have dominated combat sports such as boxing, wrestling, and mixed martial arts. These highly competitive sports are exciting, and readers learn it takes discipline, technique, and a knowledge of the ...
Spilsbury, Louise.
core  

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

open access: yesAdvanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv   +14 more
wiley   +1 more source

Report on combat poverty led consultation process for people living in vulnerable circumstances

open access: yes, 2006
In the context of its role in supporting consultation on the National Action Plan against Poverty and Social Inclusion 2006-2008 (NAP/Inclusion), the Combat Poverty Agency undertook to organise a consultation process focusing on the poverty issues ...
Combat Poverty Agency
core  

Rare‐Earth–Sulfur Surface Modification Enables SiC Ceramics for Low‐Frequency Electromagnetic Wave Absorption in Extreme Environments

open access: yesAdvanced Science, EarlyView.
By altering surface chemical bonds to prolong relaxation time and shift absorption to lower frequencies, SiC/rare earth–sulfur (RE─S, RE = La, Ce, Pr, Sm, Gd, Er) materials achieve excellent low‐frequency electromagnetic wave absorption under extreme conditions, offering a new direction for designing high‐performance SiC‐based absorbers.
Zhanming Wu   +5 more
wiley   +1 more source

A Novel, Sport-Specific EMG-Based Method to Evaluate Movement Efficiency in Karate Punching

open access: yesSports
Background: This study aimed to develop a method to analyze the kinetic and kinematic characteristics of the traditional karate Gyaku Tsuki (reverse punch), focusing on the activation sequence of lower and upper extremities and trunk muscles during ...
László Csákvári   +2 more
doaj   +1 more source

Initiation to combat sports through a Constraints-Led Approach [PDF]

open access: yes
[EN] This presentation introduces an initiation into combat sports based on a motor learning model known as ecological dynamics that informs the Constraints-led Approach (CLA) to teaching.
Sánchez García, Raúl
core  

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng   +6 more
wiley   +1 more source

Two‐Dimensional Conjugated Metal Organic Frameworks with Dual Metal Catalytic Active Sites Enhance POD Activity for Antibacterial Treatment

open access: yesAdvanced Science, EarlyView.
A new class of Cu, Ni bimetallic 2D cMOF (CuNi‐HHTP 2D cMOF) featuring dual catalytic sites and high delocalized electronic structure for boosting POD performance. The CuNi‐HHTP 2D‐cMOF enhances the conversion kinetics of H2O2 to ROS, which subsequently enhances antibacterial activity and accelerates the healing of oral ulcers, with macroscopic wound ...
Yixuan Lu   +9 more
wiley   +1 more source

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