Results 101 to 110 of about 20,615 (252)

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source

Social Physique Anxiety Levels of Turkish Combat Sports (Martial Arts) Athletes and Sedentary Individuals

, 2019
Background and Study Aim: Anxiety is one's threat perception and fear of an outer situation-specific event generally accompanied by an expectation of future threat.
Sertbas, Kursad, Sivrikaya, Kenan, Calik, Fehmi, Geri, Serdar, Yalcin, Ilimdar   +4 more
core   +1 more source

Woman in combat sports

, 2020
Borilački sportovi su polistrukturalne acikličke aktivnosti u kojima je cilj stvarna ili simbolička destrukcija protivnika. Često se raspravlja potiču li borilački sportovi agresivno ponašanje ili upravo suprotno, djeluje li treniranje borilačkih ...
Petrić, Valentina
core  

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Extrinsic feedback in martial arts training

Revista de Artes Marciales Asiáticas, 2016
Michal Vít, Zdenko Reguli, Jitka Cihounkova   +2 more
doaj   +1 more source

The impact of the collision training use of the arms on some special physical variables and the skillful performance of boxing beginners [PDF]

Assiut Journal of Sport Science and Arts, 2016
Mohamed Zakaria Baldam
doaj   +1 more source

The expression of aggression in combat sport of youngster and youth.

, 2011
The scientific problem is the fact that sporting activity is a social phenomenon, which gets aggressive actions, particularly related to combat sports. Therefore, the difficulty posed by the question of what a combat sport, youth and juniors, expression ...
Gediminas, Nerijus,
core  

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Carboranyl‐Curcuminoids for the Neutron Capture‐Based Treatment of Amyloid Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci, Stefano Parisotto, Diego Alberti, Alberto Lanfranco, Valeria Bitonto, Polyssena Renzi, Martina Salmi, Andrea Magnani, Federica Dal Bello, Katiuscia Pagano, Laura Ragona, Nicoletta Protti, Annamaria Deagostino, Simonetta Geninatti Crich   +13 more
wiley   +1 more source

Is dojo the spiritual place in aikido?

Revista de Artes Marciales Asiáticas, 2016
Zdenko Reguli, Michal Vít, Jitka Cihounkova   +2 more
doaj   +1 more source