Results 121 to 130 of about 1,013,319 (286)
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
Advanced Science, EarlyView.This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
Advanced Science, EarlyView.A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang +7 more
wiley +1 more source
Laterality and performance in combat sports.
, 2016 [Abstract]: Literature has shown a relationship between laterality and an over-representation of left-handed athletes in certain sports, and especially in sports one against one, such as judo, tennis, boxing or fencing; the main ex-planation has been attributed to greater chance of success.
Ardá Suárez, Antonio +5 more
openaire +1 more source
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Advanced Science, EarlyView.Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
SPECIFICS OF MOTIVATION IN COMBAT SPORTS
Sport Mont, 2012 Motivation can be defined as conscious or unconscious experience that serves as a factor that determines a person's behavior or her social action in a given situation. So far, various studies had identified over 100 different factors that explain why people engage in sports.
Jelena Ilić, Dragoljub Višnjić
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Advanced Science, EarlyView.A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv +16 more
wiley +1 more source
Sports, Inc., Volume 03, Issue 2 [PDF]
, 2011 The ILR Cornell Sports Business Society magazine is a semester publication titled Sports, Inc. This publication serves as a space for our membership to publish and feature in-depth research and well-thought out ideas to advance the world of sport.
ILR Cornell Sports Business Society
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Advanced Science, EarlyView.Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie +10 more
wiley +1 more source
Distinctiveness in combat sport aesthetics
AUC KINANTHROPOLOGICAAccording to some philosophers, sports where athletes actively struggle against their opponents are aesthetically enhanced because of the increased potential for drama arising from dynamics of social interaction. I argue that combat sports further increase the potential of such dramatic aesthetic appeal.
openaire +2 more sources
, 2018 Titleofwork: Combat sports motivation. Workobjective: The aim of this diploma thesis is to determine motives for participating in certain combat sports and to examine if the individual combat sports vary from each other or whether there is a common ...
Šimáček, Pavel
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