Results 111 to 120 of about 1,013,319 (286)
Advanced Science, EarlyView.Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger +8 more
wiley +1 more source
Disruptive situations and the development of practitioners in martial arts and combat sports: a phenomenological analysis from the perspective of the instructor [PDF]
[EN] The combative phenomenon and the violent phenomenon are closely related in Martial Arts and Combat Sports (MA&CS) (Telles et al., 2022). Understanding how this proximity manifests in fights may offer insights into the occurrence of violence in other
Santos, Maria Gabriela dos +2 more
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Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds
Advanced Science, EarlyView.This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng +14 more
wiley +1 more source
Advanced Science, EarlyView.Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu +18 more
wiley +1 more source
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
, 1988 This is the first Interim Report of the Projects in the Republic of Ireland in the Second European Programme to Combat Poverty. The projects have been meeting regularly to share experiences and information since they began their work.
Combat Poverty Agency
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Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy
Advanced Science, EarlyView.A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan +9 more
wiley +1 more source
, 2019 Background and Study Aim: Anxiety is one's threat perception and fear of an outer situation-specific event generally accompanied by an expectation of future threat.
Sertbas, Kursad +4 more
core +2 more sources
Frontiers in ChemistryTraditional combat sports equipment usually uses synthetic materials, such as polyurethane and synthetic leather. Although these materials have a certain degree of strength and durability, they have poor flexibility and antibacterial properties, making ...
Yang Lu +4 more
doaj +1 more source