Results 51 to 60 of about 4,545,331 (281)

Modified Halpern Iterative Method for Solving Hierarchical Problem and Split Combination of Variational Inclusion Problem in Hilbert Space

open access: yesMathematics, 2019
The purpose of this paper is to introduce the split combination of variational inclusion problem which combines the concept of the modified variational inclusion problem introduced by Khuangsatung and Kangtunyakarn and the split variational inclusion ...
Bunyawee Chaloemyotphong   +1 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Combination Projection Method for Solving Convex Feasibility Problems

open access: yesMathematics, 2018
In this paper, we propose a new method, which is called the combination projection method (CPM), for solving the convex feasibility problem (CFP) of finding some x * ∈ C : = ∩ i = 1 m { x ∈ H | c i ( x ) ≤ 0 } ,
Songnian He, Qiao-Li Dong
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Three-Sided Fuzzy Stable Matching Problem Based on Combination Preference

open access: yesSystems
Previous studies, constrained by the overly rigid stability requirements, often fail to adapt to complex systems and struggle to identify stable outcomes that align with the practical context of multi-agent resource allocation. To address the three-sided
Ruya Fan, Yan Chen
doaj   +1 more source

Objects of consciousness

open access: yesFrontiers in Psychology, 2014
Current models of visual perception typically assume that human vision estimates true properties of physical objects, properties that exist even if unperceived.
Donald David Hoffman, Chetan ePrakash
doaj   +1 more source

Cue combination in the motion correspondence problem [PDF]

open access: yesProceedings of the Royal Society of London. Series B: Biological Sciences, 2000
Image motion is a primary source of visual information about the world. However, before this information can be used the visual system must determine the spatio-temporal displacements of the features in the dynamic retinal image, which originate from objects moving in space. This is known as the motion correspondence problem.
P B, Hibbard, M F, Bradshaw, R A, Eagle
openaire   +2 more sources

A set oriented approach to global optimal control [PDF]

open access: yes, 2002
We describe an algorithm for computing the value function for 'all source, single destination' discrete-time nonlinear optimal control problems together with approximations of associated globally optimal control strategies.
Junge, O, Osinga, Hinke M
core  

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