Results 91 to 100 of about 28,100,614 (312)

Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria [PDF]

, 2008
Besides existing artemisinin-based combination therapies, alternative safe, effective and affordable drug combinations against falciparum malaria are needed. Methylene blue (MB) was the first synthetic antimalarial drug ever used, and recent studies have
Walter-Sack, Ingeborg, Coulibaly, Boubacar, Sié, Ali, Schirmer, R. Heiner, Zoungrana, Augustin, Meissner, Peter E., Müller, Olaf, Kouyaté, Bocar, Klose, Christina, Mockenhaupt, Frank P., Mansmann, Ulrich   +10 more
core   +1 more source

Overcoming Limitations of Cisplatin Therapy by Additional Treatment With the HSP90 Inhibitor Onalespib

Frontiers in Oncology, 2020
RationalCisplatin based cancer therapy is an affordable and effective standard therapy for several solid cancers, including lung, ovarian and head and neck cancers.
Anja Charlotte Lundgren Mortensen, Tabassom Mohajershojai, Mehran Hariri, Marika Pettersson, Diana Spiegelberg, Diana Spiegelberg   +5 more
doaj   +1 more source

Anti-VEGF Monotherapy Versus Photodynamic Therapy and Anti-VEGF Combination Treatment for Neovascular Age-Related Macular Degeneration: A Meta-Analysis.

Investigative Ophthalmology and Visual Science, 2018
Purpose The purpose of this study was to compare the efficacy and safety of anti-VEGF monotherapy with verteporfin photodynamic therapy (PDT) and anti-VEGF combination treatment in neovascular AMD.
Yang Gao, Tao Yu, Yue Zhang, G. Dang
semanticscholar   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Enzalutamide and CXCR7 inhibitor Combination Treatment Suppresses Cell Growth and Angiogenic Signaling in Castration-Resistant Prostate Cancer Models

International Journal of Cancer, 2018
Previous studies have shown that increased levels of chemokine receptor CXCR7 are associated with the increased invasiveness of prostate cancer cells.
Yong Luo, A. Azad, S. Karanika, Spyridon Panagiotis Basourakos, Xuemei Zuo, Jianxiang Wang, Y. Luan, Guang Yang, Dimitrios Korentzelos, Jianhua Yin, Sanghee Park, Peng-Lie Zhang, J. Campbell, T. Schall, Guangwen Cao, Likun Li, T. Thompson   +16 more
semanticscholar   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Experimental Evolution of Resistance to Artemisinin Combination Therapy Results in Amplification of the mdr1 Gene in a Rodent Malaria Parasite [PDF]

, 2010
Background: Lacking suitable alternatives, the control of malaria increasingly depends upon Artemisinin Combination Treatments (ACT): resistance to these drugs would therefore be disastrous.
Sanchez Cecília P., Rodrigues Louise A., Louise A. Rodrigues, Hunt Paul, Sanchez, Cecília P, Hunt, Paul, Axel Martinelli, Rodrigues, Louise A, Borges, Sofia T, Henriques, Gisela, Martinelli Axel, Cecília P Sanchez, Henriques Gisela, Cecília P. Sanchez, Louise A Rodrigues, Sofia T. Borges, Borges Sofia T., Sanchez, Cecilia P., Borges, Sofia T., Sofia T Borges, Pedro Cravo, Martinelli, Axel, Gisela Henriques, Paul Hunt, Cravo, Pedro, Cravo Pedro, Rodrigues, Louise A.   +26 more
core   +1 more source

Mirtazapine combination in treatmentresistant major depressive disorder: a retrospective evaluation of six weeks

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Despite the adequate time and dose of antidepressant treatment, approximately one-third of the patients with major depression do not respond.
Omer Aydemir, Artuner Deveci, E.Oryal Taskin   +2 more
doaj  

THE USE OF FIXED COMBINATION OF PERINDOPRIL AND AMLODIPINE IN 2ND STAGE ARTERIAL HYPERTENSION

Российский кардиологический журнал, 2015
Aim. To evaluate efficacy and safety of combination antihypertension compound Dalneva® — combination of perindopril and amlodipine by KRKA company in treatment of patients with second stage arterial hypertension (AH).Material and methods.
E. N. Andreicheva
doaj   +1 more source

Synergistic Rescue of Nonsense Mutant Tumor Suppressor p53 by Combination Treatment with Aminoglycosides and Mdm2 Inhibitors

Frontiers in Oncology, 2018
The tumor suppressor gene TP53 is inactivated by mutation in a large fraction of human tumors. Around 10% of TP53 mutations are nonsense mutations that lead to premature termination of translation and expression of truncated unstable and non-functional ...
Meiqiongzi Zhang, Angelos Heldin, Mireia Palomar-Siles, Susanne Öhlin, V. J. Bykov, K. Wiman   +5 more
semanticscholar   +1 more source