Results 101 to 110 of about 28,100,614 (312)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Clinical correlates of augmentation/combination treatment strategies in major depressive disorder

Acta Psychiatrica Scandinavica, 2018
This multicenter, multinational, cross‐sectional study aimed to investigate clinical characteristics and treatment outcomes associated with augmentation/combination treatment strategies in major depressive disorder (MDD).
M. Dold, L. Bartova, J. Mendlewicz, D. Souery, A. Serretti, S. Porcelli, J. Zohar, S. Montgomery, S. Kasper   +8 more
semanticscholar   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Naltrexone and Bupropion Combination Treatment for Smoking Cessation and Weight Loss in Patients With Schizophrenia

Frontiers in Pharmacology, 2018
Objective: The rates of obesity and cigarette smoking are much higher in patients with schizophrenia compared to the general population. This study was to examine whether naltrexone and bupropion combination treatment can help weight loss and smoking ...
Xuechan Lyu, Jiang Du, Gui-Lai Zhan, Yujie Wu, Hang Su, Youwei Zhu, F. Jarskog, Min Zhao, Xiao-Duo Fan   +8 more
semanticscholar   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Nifurtimox plus eflornithine for late-stage sleeping sickness in Uganda: A case series [PDF]

, 2007
Background: We report efficacy and safety outcomes from a prospective case series of 31 late-stage T. b. gambiense sleeping sickness (Human African Trypanosomiasis, HAT) patients treated with a combination of nifurtimox and eflornithine (N+ E) in Yumbe ...
Thomas, F, Legros, Dominique, Francesco Checchi, Patrice Piola, Thomas Florence, Ayikoru Harriet, Gerardo Priotto, Piola, P, Ayikoru, H, Piola, Patrice, Ayikoru, Harriet, Checchi Francesco, Legros, D, Thomas, Florence, Priotto Gerardo, Checchi, F, Priotto, Gerardo, Florence Thomas, Priotto, G, Checchi, Francesco, Legros Dominique, Dominique Legros, Harriet Ayikoru, Piola Patrice   +23 more
core   +2 more sources

Combination treatment with the cap-dependent endonuclease inhibitor baloxavir marboxil and a neuraminidase inhibitor in a mouse model of influenza A virus infection

Journal of Antimicrobial Chemotherapy, 2018
Objectives Baloxavir marboxil (formerly S-033188) is a first-in-class, orally available, cap-dependent endonuclease inhibitor licensed in Japan and the USA for the treatment of influenza virus infection.
K. Fukao, Takeshi Noshi, A. Yamamoto, Mitsutaka Kitano, Y. Ando, Takahiro Noda, Kaoru Baba, Kazumi Matsumoto, Naoko Higuchi, M. Ikeda, T. Shishido, Akira Naito   +11 more
semanticscholar   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. [PDF]

, 2008
BACKGROUND: Artemisinin combination therapies (ACT), which are increasingly being introduced for treatment of Plasmodium falciparum malaria, are more effective against sexual stage parasites (gametocytes) than previous first-line antimalarials and ...
Drakeley, Chris J, Bousema, Teun, Sutherland, CJ, Lucy C Okell, Bousema, T, Ghani, Azra C, Sutherland Colin J, Drakeley Chris J, Drakeley, CJ, Colin J Sutherland, Okell Lucy C, Bousema Teun, Okell, Lucy C, Azra C Ghani, Sutherland, Colin J, Ghani Azra C, Ghani, AC, Teun Bousema, Okell, LC, Chris J Drakeley   +19 more
core   +1 more source

Niclosamide and bicalutamide combination treatment overcomes enzalutamide and bicalutamide resistant prostate cancer

Molecular Cancer Therapeutics, 2017
Activation of the androgen receptor (AR) and its splice variants is linked to advanced prostate cancer and drives resistance to antiandrogens. The roles of AR and AR variants in the development of resistance to androgen deprivation therapy (ADT) and ...
Cheng-Fei Liu, C. Armstrong, W. Lou, A. Lombard, V. Cucchiara, Xinwei Gu, Joy C. Yang, N. Nadiminty, C. Pan, C. Evans, A. Gao   +10 more
semanticscholar   +1 more source