Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study. [PDF]
: BACKGROUND: Artemisinin-based combination therapy (ACT) has been promoted as a means to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasites, which sustain infections over long periods and the immature
Mwita, A. +106 more
core +1 more source
Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda. [PDF]
BACKGROUND: Drug resistance in Plasmodium falciparum poses a major threat to malaria control. Combination antimalarial therapy including artemisinins has been advocated recently to improve efficacy and limit the spread of resistance, but artemisinins are
Albert Kilian +59 more
core +2 more sources
Introduction Peripheral nerve injury (PNI) often leads to significant functional loss in patients and poses a challenge to physicians since treatment options for improving functional outcomes are limited.
Jung Il Lee +3 more
semanticscholar +1 more source
Are Tanzanian patients attending public facilities or private retailers more likely to adhere to artemisinin-based combination therapy? [PDF]
BACKGROUND: Artemisinin combination therapy (ACT) is first-line treatment for malaria in most endemic countries and is increasingly available in the private sector. Most studies on ACT adherence have been conducted in the public sector, with minimal data
Catherine Goodman +17 more
core +1 more source
Gemcitabine: Progress in the treatment of pancreatic cancer [PDF]
Unresectable pancreatic cancer has a dismal prognosis with a median survival of 3-5 months in untreated disease. Since the introduction of gemcitabine, pancreatic cancer may no longer be regarded a chemotherapy-resistant tumor.
Heinemann, Volker
core +1 more source
Phytochemicals are promising antibacterials for the development of novel antibiofilm drugs, but their antibiofilm activity in physiologically relevant model systems is poorly characterized.
Wen Wang +6 more
doaj +1 more source
Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment
This randomized clinical trial analyzes whether exercise, glucagon-like peptide-1 (GLP-1) receptor agonist treatment, or their combination preserve site-specific bone mineral density for individuals with obesity undergoing weight loss intervention.
S. Jensen +13 more
semanticscholar +1 more source
Beclomethasone/formoterol versus budesonide/formoterol combination therapy in asthma
The present study was designed to compare the fixed combination of beclomethasone and formoterol in a hydrofluoroalkane Modulite (Chiesi Farmaceutici, Parma, Italy) pressurised metered-dose inhaler (pMDI), with a combination of budesonide and formoterol ...
Vignola A. M. +5 more
core +1 more source
Pharmacovigilance of antimalarial treatment in Africa: is it possible? [PDF]
Pharmacovigilance, defined as "the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other possible drug related problem", is increasingly being recognized in Africa.
Talisuna, Ambrose O +11 more
core +1 more source
The role and mechanism of vascular wall cell ion channels in vascular fibrosis remodeling
Fibrosis is usually the final pathological state of many chronic inflammatory diseases and may lead to organ malfunction. Excessive deposition of extracellular matrix (ECM) molecules is a characteristic of most fibrotic tissues.
Xiaolin Zhang +5 more
doaj +1 more source

