Results 21 to 30 of about 28,100,614 (312)

Photodynamic Therapy and Hyperthermia in Combination Treatment—Neglected Forces in the Fight against Cancer

Pharmaceutics, 2021
Cancer is one of the leading causes of death in humans. Despite the progress in cancer treatment, and an increase in the effectiveness of diagnostic methods, cancer is still highly lethal and very difficult to treat in many cases. Combination therapy, in
Aleksandra Bienia, Olga Wiecheć-Cudak, A. Murzyn, M. Krzykawska-Serda   +3 more
semanticscholar   +1 more source

Synergistic Enhancement of Cancer Therapy Using HDAC Inhibitors: Opportunity for Clinical Trials

Frontiers in Genetics, 2020
Chemotherapy is one of the most established and effective treatments for almost all types of cancer. However, the elevated toxicity due to the non-tumor-associated effects, development of secondary malignancies, infertility, radiation-induced fibrosis ...
Lourdes Hontecillas-Prieto, Rocío Flores-Campos, Andrew Silver, Enrique de Álava, Enrique de Álava, Nabil Hajji, Daniel J. García-Domínguez   +6 more
doaj   +1 more source

Leukocyte/platelet hybrid membrane-camouflaged dendritic large pore mesoporous silica nanoparticles co-loaded with photo/chemotherapeutic agents for triple negative breast cancer combination treatment

Bioactive Materials, 2021
Triple-negative breast cancer (TNBC) is an aggressive subset of breast cancer and currently lacks effective therapeutic targets. As two main phototherapeutic methods, photothermal therapy (PTT) and photodynamic therapy (PDT) show many advantages in TNBC ...
Tao Zhang, Hui Liu, Ling Li, Zhaoyang Guo, Jia Song, Xiao-Ying Yang, Guo-Yun Wan, Rong-Shan Li, Yinsong Wang   +8 more
semanticscholar   +1 more source

Artemisinin-Type Drugs in Tumor Cell Death: Mechanisms, Combination Treatment with Biologics and Nanoparticle Delivery

Pharmaceutics, 2022
Artemisinin, the most famous anti-malaria drug initially extracted from Artemisia annua L., also exhibits anti-tumor properties in vivo and in vitro. To improve its solubility and bioavailability, multiple derivatives have been synthesized.
Xinyu Zhou, Fengzhi Suo, Kristina Haslinger, Wim J. Quax   +3 more
doaj   +1 more source

In Vitro Evaluation of ALDH1A3-Affinic Compounds on Breast and Prostate Cancer Cell Lines as Single Treatments and in Combination with Doxorubicin

Current Issues in Molecular Biology, 2023
Aldehyde dehydrogenase (ALDH) enzymes are involved in the growth and development of several tissues, including cancer cells. It has been reported that targeting the ALDH family, including the ALDH1A subfamily, enhances cancer treatment outcomes ...
Osama H. Abusara, Ali I. M. Ibrahim, Hamzah Issa, Alaa M. Hammad, Worood H. Ismail   +4 more
doaj   +1 more source

Combination treatment with rituximab, low-dose cyclophosphamide and plasma exchange for severe antineutrophil cytoplasmic antibody-associated vasculitis.

Kidney International, 2021
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis can present with life-threatening lung-kidney syndromes. However, many controlled treatment trials excluded patients with diffuse alveolar hemorrhage or severely impaired glomerular ...
K. Gulati, H. Edwards, M. Prendecki, T. Cairns, Marie B. Condon, J. Galliford, M. Griffith, J. Levy, Frederick W. K. Tam, A. Tanna, C. Pusey, S. McAdoo   +11 more
semanticscholar   +1 more source

Artemisinin combination therapies for treatment of uncomplicated malaria in Uganda. [PDF]

, 2006
OBJECTIVES: To compare the efficacy and safety of artemisinin combination therapies for the treatment of uncomplicated falciparum malaria in Uganda. DESIGN: Randomized single-blind controlled trial.
Staedke Sarah G, Rosenthal, Philip J, Yeka, Adoke, Banek, Kristin, Yeka Adoke, Dorsey, Grant, Staedke, Sarah G, Bakyaita Nathan, Dorsey Grant, Banek Kristin, Bukirwa, Hasifa, Talisuna Ambrose, Rosenthal Philip J, Talisuna, Ambrose, Rwakimari, John Bosco, Kamya Moses R, Kamya, Moses R, Bukirwa Hasifa, Wabwire-Mangen Fred, Bakyaita, Nathan, Wabwire-Mangen, Fred, Rwakimari John Bosco   +21 more
core   +1 more source

The efficacy of combining fractional CO2 laser and tacrolimus ointment in the treatment of vitiligo

Journal of the Egyptian Women’s Dermatologic Society, 2020
Background Treatment of vitiligo is very challenging. Topical tacrolimus is one of the topical modalities reported to be successful. No single treatment, however, gives on its own satisfactory results, and combination treatments offer better outcomes ...
Ola M Abu Zeid, Noha Omar, Dina El Sharkawy   +2 more
doaj   +1 more source

Inhibition of Poly(ADP-Ribose) polymerase enhances the toxicity of 131I-Metaiodobenzylguanidine/Topotecan combination therapy to cells and xenografts that express the noradrenaline transporter [PDF]

, 2012
Targeted radiotherapy using [131I]meta-iodobenzylguanidine ([131I]MIBG) has produced remissions in some neuroblastoma patients. We previously reported that combining [131I]MIBG with the topoisomerase I (Topo-I) inhibitor topotecan induced long-term DNA ...
McCluskey, Anthony G, Babich, John W, Champion, Sue, Mairs, Robert J, Boyd, Marie, Gaze, Mark N, Tesson, Mathias, Pimlott, Sally L   +7 more
core   +4 more sources

The efficacy of antimalarial monotherapies, sulphadoxine-pyrimethamine and amodiaquine in East Africa: implications for sub-regional policy. [PDF]

, 2003
Between 1998 and 2001, Kenya, Uganda, Tanzania, Zanzibar, Rwanda and Burundi changed antimalarial drug policy, in the face of widespread chloroquine resistance.
East African Network for Monitoring Antimalarial Treatment (EANMAT), East African Network for Monitoring Antimalarial Treatment (EANM   +1 more
core   +1 more source