Results 181 to 190 of about 436,297 (318)

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Performance Prediction of High-Entropy Perovskites La_0.8Sr_0.2Mn_xCo_yFe_zO₃ with Automated High-Throughput Characterization of Combinatorial Libraries and Machine Learning. [PDF]

Adv Mater
Bozal-Ginesta C, Sirvent J, Cordaro G, Fearn S, Pablo-García S, Chiabrera F, Choi C, Laa L, Núñez M, Cavallaro A, Buzi F, Aguadero A, Dezanneau G, Kilner J, Morata A, Baiutti F, Aspuru-Guzik A, Tarancón A.   +17 more
europepmc   +1 more source

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

A novel combinatorial approach integrating experimental and computational analysis of antioxidant activity: Evaluating catechin and L-ascorbic acid in serum. [PDF]

PLoS One
Rasool A, Chidi C, Rigaut S, Carty S, Soubra-Ghaoui C, Chandra R.   +5 more
europepmc   +1 more source

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Evaluation of dosimetric and spatial accuracy of a virtual cone technique for radiosurgery using linac‐integrated CBCT‐based polymer gel dosimetry

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study evaluates the dosimetric and geometric precision of a virtual cone technique using CBCT‐based polymer gel dosimetry, enabling radiation delivery, and imaging readout within an identical spatial coordinate system. Methods We created a C# script for a virtual cone technique that generates a treatment plan with 10 gantry arcs ...
Tenzin Kunkyab, Michael Lamey, Andrew Jirasek, Michael Kudla, Nathan Becker, Benjamin Mou, Derek Hyde   +6 more
wiley   +1 more source

The power of DNA-encoded chemical libraries in the battle against drug-resistant bacteria. [PDF]

RSC Adv
Sibai RE, Farahat ZEM, Qasem HH, Hassan H.   +3 more
europepmc   +1 more source

Design and validation of a novel dosimetry phantom for motion management audits

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background We present a novel phantom design for conducting end‐to‐end dosimetry audits for respiratory motion management of two anatomical treatment sites. The design enables radiochromic film measurements of the dose administered to the target throughout the respiratory cycle (motion‐included) and the dose delivered to the time‐averaged ...
Alex Burton, Sabeena Beveridge, Nicholas Hardcastle, Silvio Malfitana, Janaka Madamperuma, Rick Franich   +5 more
wiley   +1 more source

Recommending reaction conditions with label ranking. [PDF]

Chem Sci
Shim E, Tewari A, Cernak T, Zimmerman PM.   +3 more
europepmc   +1 more source

Empowering young minds through STEM education: Engaging high schoolers in Ghana through medical physics

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To promote diversity in Science, Technology, Engineering, and Mathematics (STEM), an educational presentation and hands‐on session was organised to raise awareness of STEM career opportunities among high school girls to introduce the students to the field of medical physics. Materials and Methods The study involved 65 first‐year Senior
Afua A. Yorke, Mercy T. Schandorf, Abigail N. M. Quaye, Peniel Tenkorama Twum, Bishwambhar Sengupta, Kwadwo Nkansah‐Poku, Juliana A. Kplorfia, Jessica Fagestrom   +7 more
wiley   +1 more source