Results 231 to 240 of about 172,692 (298)

Advances, opportunities, and challenges in methods for interrogating the structure activity relationships of natural products.

Nat Prod Rep
Ancajas CMF, Oyedele AS, Butt CM, Walker AS.   +3 more
europepmc   +1 more source

Combinatorial chemistry synthesis techniques

Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136), 2002
As pharmaceutical companies race to find new and novel drugs faster, the tools of combinatorial chemistry are increasingly playing a larger role. Chemists can now prepare hundreds or thousands of analogs simultaneously to reveal structure-activity relationships (SAR) all at once and potentially shorten the discovery process for new drugs by years.
Michael L. Vazquez
semanticscholar   +4 more sources

ChemInform Abstract: Resin Capture Techniques in Combinatorial Chemistry

ChemInform, 2000
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Alexander Chucholowski, Matthias Nettekoven   +1 more
semanticscholar   +4 more sources

High-resolution NMR techniques for solid-phase synthesis and combinatorial chemistry

Drug Discovery Today, 1997
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Paul A. Keifer
semanticscholar   +5 more sources

Analytical Techniques for Combinatorial Chemistry: Quantitative Infrared Spectroscopic Measurements of Deuterium-Labeled Protecting Groups

Journal of the American Chemical Society, 1996
Infrared microspectroscopy has been developed as a powerful, nondestructive technique for the quantitative analysis of solid-phase, resin-bound chemical reactions. The synthesis and/or application of deuterium isotope containing protecting groups, including acetyl-d3 chloride, benzoyl-d5 chloride, and 2-[[[(tert-butyl-d9)oxy]carbonyl]oximino]-2 ...
Keith C. Russell, Derek C. Cole, Frances M. McLaren, Don E. Pivonka   +3 more
semanticscholar   +4 more sources

UZM-13, UZM-17, UZM-19 and UZM-25: synthesis and structure of new layered precursors and a zeolite discovered via combinatorial chemistry techniques

, 2007
Abstract A combinatorial chemistry investigation screening the abilities of the diethyldimethylammonium (DEDMA), ethyltrimethylammonium (ETMA), and [Me 3 N(CH 2 ) 4 NMe 3 ] 2+ (diquat-4, DQ-4) cations to form zeolites over a range of conditions was carried out.
Lisa M. Knight, Mark A. Miller, Susan Koster, Michael G. Gatter, Annabelle I. Benin, Richard R. Willis, Gregory J. Lewis, Robert W. Broach   +7 more
semanticscholar   +4 more sources

Combinatorial chemistry methods for coating development VI. Correlation of high throughput screening methods with conventional measurement techniques

Progress in Organic Coatings, 2003
Abstract Combinatorial chemistry has proven to be a valuable tool for the development of new compounds. In the pharmaceutical industry, where combinatorial chemistry began, the approach has been instrumental in the high-speed development of new drugs.
Bret J. Chisholm
semanticscholar   +4 more sources