Results 21 to 30 of about 72,837 (274)

Combinatorial structures to construct simple games and molecules [PDF]

open access: yes, 2017
We connect three different topics: combinatorial structures, game theory and chemistry. In particular, we establish the bases to represent some simple games, defined as influence games, and molecules, defined from atoms, by using ...
Molinero Albareda, Xavier
core   +2 more sources

Versatile Monitoring Tools in Parallel Solid-Phase Synthesis

open access: yesCHIMIA, 2003
Parallel synthesis on solid-phase is routinely applied in our combinatorial chemistry efforts for lead finding and lead optimization in drug discovery.
Eduard R. Felder   +3 more
doaj   +1 more source

Prediction of the functional properties of ceramic materials from composition using artificial neural networks [PDF]

open access: yes, 2007
We describe the development of artificial neural networks (ANN) for the prediction of the properties of ceramic materials. The ceramics studied here include polycrystalline, inorganic, non-metallic materials and are investigated on the basis of their ...
Alford, N. Mc N.   +4 more
core   +2 more sources

DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution.

open access: yesPLoS Biology, 2004
Biological in vitro selection techniques, such as RNA aptamer methods and mRNA display, have proven to be powerful approaches for engineering molecules with novel functions.
David R Halpin, Pehr B Harbury
doaj   +1 more source

Supercritical fluid technology for solubilization of poorly water soluble drugs via micro- and naonosized particle generation

open access: yesADMET and DMPK, 2020
Approximately two-third of the compounds in the pharmaceutical industry were developed through combinatorial chemistry and high throughput screening of particulate solids.
Shashi Kiran Misra, Kamla Pathak
doaj   +1 more source

Combinatorial synthesis of oxysulfides in the lanthanum-bismuth-copper system [PDF]

open access: yes, 2020
Establishing synthesis methods for a target material constitutes a grand challenge in materials research, which is compounded with use-inspired specifications on the format of the material.
Gregoire, John M.   +6 more
core  

Upgrading SELEX Technology by Using Lambda Exonuclease Digestion for Single-Stranded DNA Generation

open access: yesMolecules, 2009
The generation of single-stranded DNA (ssDNA) molecules plays a key role in the SELEX (Systematic Evolution of Ligands by EXponential enrichment) combinatorial chemistry process and numerous molecular biology techniques and applications, such as DNA ...
Meltem Avci-Adali   +4 more
doaj   +1 more source

Ultrasonic surface acoustic wave-assisted separation of microscale droplets with varying acoustic impedance

open access: yesUltrasonics Sonochemistry, 2023
In droplet-based microfluidic platforms, precise separation of microscale droplets of different chemical composition is increasingly necessary for high-throughput combinatorial chemistry in drug discovery and screening assays.
Mushtaq Ali, Jinsoo Park
doaj   +1 more source

Isolation of antigen-specific, disulphide-rich knob domain peptides from bovine antibodies.

open access: yesPLoS Biology, 2020
As a novel alternative to established surface display or combinatorial chemistry approaches for the discovery of therapeutic peptides, we present a method for the isolation of small, cysteine-rich domains from bovine antibody ultralong complementarity ...
Alex Macpherson   +9 more
doaj   +1 more source

Microbial Identification, High-Resolution Microscopy and Spectrometry of the Rhizosphere in Its Native Spatial Context

open access: yesFrontiers in Plant Science, 2021
During the past decades, several stand-alone and combinatorial methods have been developed to investigate the chemistry (i.e., mapping of elemental, isotopic, and molecular composition) and the role of microbes in soil and rhizosphere.
Chaturanga D. Bandara   +5 more
doaj   +1 more source

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