Results 111 to 120 of about 9,474,722 (291)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Hybrid Technique Using Combinatorial Cyclic Difference Sets and Binomial Amplitude Tapering for Linear Sparse Array Antenna Design

open access: yesAdvanced Electromagnetics, 2016
Reducing system complexity and cost in synthesizing a sparse array antenna design is a challenging task for practical communication systems, such as radar systems and space communication.
E. Sandi, F. Y. Zulkifli, E. T. Rahardjo
doaj   +1 more source

Combinatorial Diffusion Auction Design

open access: yesCoRR
Diffusion auction design for combinatorial settings is a long-standing challenge. One difficulty is that we cannot directly extend the solutions for simpler settings to combinatorial settings (like extending the Vickrey auction to VCG in the traditional settings).
Xuanyu Li   +3 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Price-Based Combinatorial Auction: Connectedness and Representative Valuations [PDF]

open access: yes
We investigate combinatorial auctions from a practical perspective. The auctioneer gathers information according to a dynamical protocol termed ask price procedure.
Hitoshi Matsushima
core  

Requests from Companies and Requirements for Design Education in Brazil: where do they meet? [PDF]

open access: yes, 2018
In this paper, we study what companies request from applicants for graphic design positions in Brazil. Based on a document analysis of 371 job advertisements, we uncover 35 different types of requests which we structure in terms of (1) Design ...
Person, Oscar   +10 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Efficient DNA-based data storage using shortmer combinatorial encoding

open access: yesScientific Reports
Data storage in DNA has recently emerged as a promising archival solution, offering space-efficient and long-lasting digital storage solutions. Recent studies suggest leveraging the inherent redundancy of synthesis and sequencing technologies by using ...
Inbal Preuss   +3 more
doaj   +1 more source

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