Results 71 to 80 of about 1,967,671 (302)
Combinatorial Optimization in Cryptography
The known attacks on different cryptosystems lead to a number of criteria that the implemented cryptographic algorithms (ciphers) must satisfy. The design of cryptographic systems needs to consider various characteristics simultaneously, which can be regarded as a multi-objective combinatorial optimization problem.
openaire +4 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A Three-Stage Annealing Method Solving Slot-Placement Problems Using an Ising Machine
Ising machines are promising alternatives to solve combinatorial optimization problems, which search for their quasi-optimal solutions with high speed and high accuracy.
Keisuke Fukada +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
OPTIMIZATION FOR ONE CLASS OF COMBINATORIAL PROBLEMS UNDER UNCERTAINTY
We formalize uncertainty and compromise solution concepts, compromise criteria and conditions for a sufficiently common class of combinatorial optimization problems which functional contains a linear convolution of weights and of arbitrary numerical ...
A. A. Pavlov
doaj +1 more source
Combinatorial representations [PDF]
23pp. Submitted to J. Combinatorial Theory (Series A)arXiv:1109.1216v1 [math.CO]23pp. Submitted to J. Combinatorial Theory (Series A)23pp. Submitted to J.
Maximilien Gadouleau +10 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multimode extensions of combinatorial optimization problems [PDF]
We review some complexity results and present a viable heuristic approach based on the Variable Neighborhood Search (VNS) framework for multimode extension of combinatorial optimization problems, such as the the Set Covering Problem (SCP) and the ...
Lulli, Guglielmo +3 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

