Results 131 to 140 of about 5,770,503 (368)

Case report: Advanced age at transplantation and pre-emptive treatment with dupilumab in DOCK8 deficiency

Frontiers in Immunology
Dedicator of cytokinesis 8 (DOCK8) deficiency is a combined immunodeficiency (CID) due to biallelic mutations in the gene encoding DOCK8. Major clinical phenomena are recurrent severe infections of the lungs and skin, atopic eczema, and predisposition to
Sophia Trombello, Sophia Trombello, Andrea Jarisch, Andre Willasch, Eva Rettinger, Julia Fekadu-Siebald, Dirk Holzinger, Dirk Holzinger, Roland Adelmann, Peter Bader, Shahrzad Bakhtiar   +10 more
doaj   +1 more source

Newborn Screening for Severe Combined Immunodeficiency in the US: Current Status and Approach to Management

International Journal of Neonatal Screening, 2017
In the US, the assay of T cell receptor excision circles (TRECs) in newborn dried blood spot specimens to detect severe combined immunodeficiency (SCID) was first piloted in 2008 in the state of Wisconsin.
M. Dorsey, J. Puck
semanticscholar   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Long-term neurocognitive function of pediatric patients with severe combined immune deficiency (SCID): pre- and post-hematopoietic stem cell transplant (HSCT). [PDF]

, 2009
BACKGROUND:Hematopoietic stem cell transplantation (HSCT) is the only cure for patients with severe combined immunodeficiency (SCID). The purpose of this study was to evaluate long-term neurodevelopment of patients with SCID following myeloablative ...
Azen, Colleen, Epport, Karen, Kohn, Donald B, Lin, Malinda, Parkman, Robertson, Shah, Ami J   +5 more
core  

Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR [PDF]

, 2019
The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who ...
Berenguer, Juan, Carrero, Ana, Crespo, Manuel, González García, Juan, Guardional, Josep M., Gómez, Julián, Jiménez Sousa, María Angeles, Martínez, Isidoro, Resino, Salvador, Santos, Ignacio de los, The GESIDA 3603b Cohort Study Group, Vigón, Lorena, Von Wichmann, Miguel A., Vázquez Morón, Sonia, Yélamos, María Belén   +14 more
core   +4 more sources

Geometrically Tunable Scaffold‐Free Muscle Bioconstructs for Treating Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss is associated with traumatic muscle resulting in permanent functional impairment. Mold‐based, scaffold‐free, high‐density muscle tissue bioconstructs are developed in customizable geometric shapes and sizes. The transplanted rectangular solid‐shaped muscle bioconstructs improved muscle force recovery and tissue regeneration in ...
Bugra Ayan, Gaoxian Chen, Ishita Jain, Sha Chen, Gladys Chiang, Caroline Hu, Renato Reyes, Beu P. Oropeza, Ngan F. Huang   +8 more
wiley   +1 more source

Severe Combined Immunodeficiency due to NHEJ1 Deficiency [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Loss of DIAPH1 causes SCBMS, combined immunodeficiency and mitochondrial dysfunction.

Journal of Allergy and Clinical Immunology, 2021
Meri Kaustio, Naemeh Nayebzadeh, R. Hinttala, T. Tapiainen, P. Åström, Katariina Mamia, Nora Pernaa, J. Lehtonen, V. Glumoff, E. Rahikkala, Minna Honkila, P. Olsen, A. Hassinen, Minttu Polso, Nashat Al Sukaiti, Jalila Al Shekaili, Mahmood Al Kindi, Nadia Al Hashmi, H. Almusa, Daria R Bulanova, E. Haapaniemi, Pu Chen, Maria H Suo-Palosaari, Päivi M Vieira, H. Tuominen, H. Kokkonen, Nabil Al Macki, Huda Al Habsi, T. Löppönen, H. Rantala, V. Pietiäinen, Shen-Ying Zhang, M. Renko, T. Hautala, Tariq Al Farsi, J. Uusimaa, J. Saarela   +36 more
semanticscholar   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Antiretroviral therapy to prevent HIV acquisition in serodiscordant couples in a hyperendemic community in rural South Africa [PDF]

, 2016
Background. Antiretroviral therapy (ART) was highly efficacious in preventing human immunodeficiency virus (HIV) transmission in stable serodiscordant couples in the HPTN-052 study, a resource-intensive randomized controlled trial with near-perfect ART ...
Bärnighausen, Till, De Gruttola, Victor, Harling, Guy, Iwuji, Collins C, Mayer, Kenneth H, Mimiaga, Matthew J, Oldenburg, Catherine E, Pillay, Deenan, Seage III, George R, Tanser, Frank   +9 more
core   +3 more sources