Results 191 to 200 of about 5,770,503 (368)

A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency.

Journal of Allergy and Clinical Immunology, 2019
S. Volpi, M. Cicalese, P. Tuijnenburg, A. Tool, E. Cuadrado, Marwan Abu-Halaweh, H. Ahanchian, Raed Alzyoud, Z. Akdemir, F. Barzaghi, A. Blank, B. Boisson, C. Bottino, I. Brigida, R. Caorsi, J. Casanova, S. Chiesa, Ivan K. Chinn, G. Dückers, A. Enders, H. C. Erichsen, L. Forbes, T. Gambin, M. Gattorno, E. G. Karimiani, S. Giliani, M. Gold, Eva Jacobsen, Machiel H. Jansen, Jovanka R. King, R. Laxer, J. Lupski, E. Mace, S. Marcenaro, R. Maroofian, A. Meijer, T. Niehues, L. Notarangelo, J. Orange, U. Pannicke, C. Pearson, P. Picco, P. Quinn, A. Schulz, F. Seeborg, A. Stray-Pedersen, Hasan Tawamie, E. V. van Leeuwen, A. Aiuti, R. Yeung, K. Schwarz, T. Kuijpers   +51 more
semanticscholar   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Severe combined immunodeficiency caused by a new homozygous RAG1 mutation with progressive encephalopathy

, 2013
Nivedita Dhingra, Satya Prakash Yadav, Jean‐Pierre de Villartay, Capucine Pïcard, RK Sabharwal, Véronique Dinand, Samarjit Singh Ghuman, Anupam Sachdeva   +7 more
openalex   +1 more source

“DISAPPEARING BILE DUCT SYNDROME,” RESULT OF A GRAFT VERSUS HOST (GvsH) REACTION, AFTER FETAL LIVER AND THYMUS TRANSPLANTATION FOR SEVERE COMBINED IMMUNODEFICIENCY DISEASE (SCID) [PDF]

, 1977
Flossie Cohen, Rukmani Raghunath, Chester M. Zmijewski, Eugene V. Perrin, A. Joseph Brough   +4 more
openalex   +1 more source

Severe Combined Immunodeficiency [PDF]

JAMA, 2013
Ann R. Punnoose, Cassio Lynm, Robert M. Golub   +2 more
openaire   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Severe Combined Immunodeficiency: A Case Series and Review from a Tertiary Pediatric Hospital

Iranian Journal of Allergy, Asthma and Immunology, 2018
Severe combined immunodeficiency syndrome (SCID) is a life-threatening condition leading to early infant death as a result of severe infection, due to impaired cellular and humoral immune systems.
Shahrzad Fallah, Mehrnaz Mesdaghi, Mahboubeh Mansouri, Delara Babaei, Abdollah Karimi, Seyed Alireza Fahimzad, Shahnaz Armin, Sedigheh Rafiei Tabatabaei, Roxana Azma, Ghamartaj Khanbabaee, Bahram Bashardoost, Mehrdad Amirmoeini, Saeed Sadr, Rozita Jalilianhasanpour, Roxana Ghanaei, Nima Rezaei, Zahra Chavoshzadeh   +16 more
doaj  

Molecular genetics of common variable immunodeficiency

, 2017
Bogaert, Delfien, De Baere, Elfride, Dullaers, Melissa, Haerynck, Filomeen   +3 more
core   +1 more source

Deep Learning‐Powered Scalable Cancer Organ Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
This scalable, low‐cost Organ Chip platform, made via injection molding, uses capillary pinning for hydrogel confinement and supports versatile tissue coculture and robust imaging. Deep learning enables label‐free, sensitive phenotypic analysis.
Yu‐Chieh Yuan, Beibei Xu, Jenna McCormack, XuHai Huang, Jingzhe Ma, Thomas Marshall, Yacong Sun, Hardeep Singh, Alyssa Fanelli, Gauri Kulkarni, Ji Hye Seo, Paige Gilbride, Bing Wei, Bo Wang, Yanyan Liu, Fei Ma, Lin Zhou, Shuyang Wang, Xiaohua Qian, Zhiyong Xie, Polina Golland, Longlong Si, Yu Shrike Zhang, Xin Xie, Haiqing Bai   +24 more
wiley   +1 more source

CD45-deficient severe combined immunodeficiency caused by uniparental disomy [PDF]

, 2012
Joseph L. Roberts, Rebecca H. Buckley, Biao Luo, Jianming Pei, Alla Lapidus, Suraj Peri, Qiong Wei, Jinwook Shin, Roberta Parrott, Roland L. Dunbrack, Joseph R. Testa, Xiao‐Ping Zhong, David L. Wiest   +12 more
openalex   +1 more source