Results 211 to 220 of about 5,770,503 (368)

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, EarlyView.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Targeted Next-Generation Sequencing in the Molecular Diagnosis of Severe Combined Immunodeficiency. [PDF]

Medicina (Kaunas)
Bakaros E, Sarrou S, Gkantaras A, Matziri A, Galanopoulos AP, Charisi K, Bangeas A, Taparkou A, Papadimitriou E, Mouchtouri VA, Kalala F, Hadjichristodoulou C, Speletas M, Farmaki E.   +13 more
europepmc   +1 more source

Combined Immunodeficiency Caused by a Novel Nonsense Mutation in LCK. [PDF]

J Clin Immunol, 2023
Keller B, Kfir-Erenfeld S, Matusewicz P, Hartl F, Lev A, Lee YN, Simon AJ, Stauber T, Elpeleg O, Somech R, Stepensky P, Minguet S, Schraven B, Warnatz K.   +13 more
europepmc   +1 more source

A monoallelic activating mutation in RAC2 resulting in a combined immunodeficiency.

Journal of Allergy and Clinical Immunology, 2019
V. Lougaris, J. Chou, A. Beano, Jacqueline G. Wallace, M. Baronio, L. Gazzurelli, T. Lorenzini, D. Moratto, G. Tabellini, S. Parolini, Michael Seleman, Kelsey Stafstrom, Haiming Xu, Chad Harris, R. Geha, A. Plebani   +15 more
semanticscholar   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

RETRACTED: Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

Ibrain, EarlyView., 2023
This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju, Samyuktha Villavan, Saranya Ravi, Roja Murugesan, Panneerselvam Theivendren, Vennila Jaganathan, Redlin Jani Rajan, Krupanidhi Karunanithi   +7 more
wiley   +1 more source

Neurodevelopmental outcomes following hematopoietic cell transplantation for patients with severe combined immunodeficiency (SCID): A PIDTC study. [PDF]

J Hum Immun
Brumm VL, Kidd SA, Logan BR, Chunara F, Heimall J, Griffith LM, Kohn DB, Sanchez L, Bednarski JJ, Martinez C, Lugt MV, Kapoor N, Wright N, Spitzer B, Oved JH, Chandra S, Chellapandian D, Ebens CL, Petrovic A, Rayes A, Haines HL, Lust H, Schofield HT, Christopher L, Harris LL, Satter LF, Burroughs L, Dvorak CC, Haddad E, Leiding JW, Marsh RA, Notarangelo LD, Pai SY, Pulsipher MA, Puck JM, Cowan MJ, Shah AJ.   +36 more
europepmc   +1 more source

Close linkage of the locus for X chromosome-linked severe combined immunodeficiency to polymorphic DNA markers in Xq11-q13.

, 1987
Geneviève de Saint Basile, Benoı̂t Arveiler, I. Oberlé, S Malcolm, R J Levinsky, YL Lau, Marten H. Hofker, Marianne Debré, Alain Fischer, C Griscelli   +9 more
openalex   +2 more sources

Severe combined immunodeficiency due to CTPS1 deficiency [PDF]

, 2020
INSERM
openalex   +1 more source