Results 251 to 260 of about 5,770,503 (368)

Severe Combined Immunodeficiency (SCID) and Its New Treatment Modalities. [PDF]

Cureus, 2023
Wadbudhe AM, Meshram RJ, Tidke SC.
europepmc   +1 more source

Effect of Abrogation of Natural Killer Cell Activity on the Course of Candidiasis Induced by Intraperitoneal Administration and Gastrointestinal Candidiasis in Mice with Severe Combined Immunodeficiency [PDF]

, 1993

openalex   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

First case of primary CNS lymphoma in a patient with severe combined immunodeficiency carrying a novel ZAP70 mutation: a case report. [PDF]

Ann Med Surg (Lond)
Albitar MH, Sayed AG, Joueidi F, Mariyam N, AlDamouni MB, Albalawi WA, Arnaout R.   +6 more
europepmc   +1 more source

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Hemizygous <i>IL2RG</i> Variants Impair IL-2-Induced STAT5 Phosphorylation and Transcriptional Activity Causing X-Linked Severe Combined Immunodeficiency. [PDF]

Appl Clin Genet
Zhang N, Sang YL, Zhu W, Wang YR, Yu YY, Chen YH, Du J, He WB, Tan YQ, Wang FY.   +9 more
europepmc   +1 more source

Combined immunodeficiency with EBV positive B cell lymphoma and epidermodysplasia verruciformis due to a novel homozygous mutation in RASGRP1

, 2017
Craig D. Platt, Ari J. Fried, Rodrigo Hoyos‐Bachiloglu, G. Naheed Usmani, Birgitta Schmidt, Jennifer Whangbo, Roberto Chiarle, Janet Chou, Raif S. Geha   +8 more
openalex   +2 more sources

Astute Clinician Report: A Novel 10 bp Frameshift Deletion in Exon 2 of ICOS Causes a Combined Immunodeficiency Associated with an Enteritis and Hepatitis [PDF]

, 2015
Nic Robertson, Karin R. Engelhardt, Neil V. Morgan, D Barge, Andrew J. Cant, Stephen Hughes, Mario Abinun, Yaobo Xu, Mauro Santibáñez Koref, Peter D. Arkwright, Sophie Hambleton   +10 more
openalex   +1 more source

Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype.

Blood, 2017
H. Kuehn, J. Niemela, Karthik Sreedhara, J. Stoddard, J. Grossman, Christian A. Wysocki, M. de la Morena, Mary Garofalo, Jingga Inlora, Michael P. Snyder, David B. Lewis, Constantine A. Stratakis, T. Fleisher, Sergio D. Rosenzweig   +13 more
semanticscholar   +1 more source

Editorial: Screening for Primary Immunodeficiency Disorders (PIDDs) in Neonates

Frontiers in Immunology, 2020
Elham Hossny, Antonio Condino-Neto, Lennart Hammarström, Jolan Eszter Walter, Jolan Eszter Walter, Jolan Eszter Walter   +5 more
doaj   +1 more source