Results 301 to 310 of about 5,770,503 (368)

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency. [PDF]

Lab Anim (NY)
Monarch K, Yoon J, Uh K, Reese E, Restrepo DC, de Carvalho Madrid DM, Touchard L, Spate LD, Samuel MS, Driver JP, Lim JH, Schlink S, Whitworth KM, Wells KD, Prather RS, Chen PR, Lee K.   +16 more
europepmc   +1 more source

Nanoparticles in microdroplets: Recent advances in microfluidic generators for producing functional microbeads

Droplet, EarlyView.
Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
  Bayinqiaoge, Chengchen Zhang, Shi‐Yang Tang   +2 more
wiley   +1 more source

Novel IL2RG gene mutation causing primary combined immunodeficiency disease: A case report and literature review. [PDF]

Cent Eur J Immunol
Cao F, Shi Y, Deng F, Yan Y.
europepmc   +1 more source

Improvement of natural killer activity and of T cells after thymopoietin pentapeptide therapy in a patient with severe combined immunodeficiency.

, 1981
Massimo Fiorilli, Maria Caterina Sirianni, Franco Pandolfi, Isabella Quinti, U Tosti, F Aiuti, Gideon Goldstein   +6 more
openalex   +1 more source

Effect of Cultured Thymic Epithelium Transplantation in a Patients with Severe Combined Immunodeficiency [PDF]

, 1992
Soo Kyung Yun, Byoung Ho, Woo Seung Jeoun, Dong Soo Kim   +3 more
openalex  

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Multi-Year Registry Study of Elapegademase Treatment in Patients With Adenosine Deaminase Severe Combined Immunodeficiency (ADA-SCID) Requiring Enzyme Replacement Therapy. [PDF]

J Clin Immunol
Dorsey MJ, Butte MJ, Lieberman JA, Lehman H, Fausnight T, Keller MD, Fradette C, Hershfield MS, Pozos TC, Rozova A, Wall LA, Bednarski JJ, Tarrant TK, Chong HJ, Geng B, Temin NT, Laubach SS, Lin L, Mousallem T, Walter JE.   +19 more
europepmc   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source