Results 51 to 60 of about 257,026 (346)

Clinical Analysis of 45 Patients with Thymic Carcinoma

Cancer Biology & Medicine, 2009
OBJECTIVE To retrospectively evaluate the prognostic factors for advanced thymic carcinoma. METHODS The data from 45 patients with advanced thymic carcinoma were retrospectively analyzed according to Masaoka stage criteria.
Ruitai FAN, Jingmin WANG, Hongzhi ZHANG
doaj   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Primary endocrine therapy of locally advanced breast cancer patients [PDF]

Archive of Oncology, 2003
Primary endocrine therapy has been traditionally reserved for elderly and unfit locally advanced breast cancer patients (LABC patients). In this group, the primary endocrine therapy could not be adequately compared to primary chemotherapy.
Nešković-Konstantinović Zora B.
doaj   +1 more source

Multimodality Treatment with Conventional Transcatheter Arterial Chemoembolization and Radiofrequency Ablation for Unresectable Hepatocellular Carcinoma [PDF]

, 2012
Background/Aims: To evaluate the efficacy of multimodality treatment consisting of conventional transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) in patients with non-resectable and non-ablatable hepatocellular carcinoma ...
Albrecht T, Bloomston M, Bosch FX, Bruix J, Bruix J, Buscarini E, Buscarini L, Buscarini L, C. Trumm, Camma C, Clasen S, Dupuy DE, El-Serag HB, F. Bamberg, F.T. Kolligs, Geschwind JF, Jemal A, Kagawa T, Kettenbach J, Kim JH, Kirikoshi H, Lencioni R, Lencioni R, Lencioni R, Lencioni RA, Lin SM, Lin SM, Livraghi T, Livraghi T, Llovet JM, Llovet JM, Lo CM, M. Rentsch, M.F. Reiser, Marelli L, Marrero JA, N. Ashoori, Oken MM, P. Paprottka, Parkin DM, Poon RT, Rossi S, Sherman M, Shiina S, T.F. Jakobs, Veltri A, Vetter D, Yamakado K, Zhang L   +48 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

The Role of Chemotherapy and Radiotherapy in the Surgical Management of Muscle Invasive Bladder Cancer

International Journal of Medical Students, 2014
The management of muscle invasive bladder cancer represents an unresolved clinical challenge. Invasive urothelial carcinomas are associated with high mortality rates and early metastatic disease.
Joshua Luck
doaj   +1 more source

Long-Term Experience of Chemoradiotherapy Combined with Deep Regional Hyperthermia for Organ Preservation in High-Risk Bladder Cancer (Ta, Tis, T1, T2). [PDF]

, 2019
BackgroundThe aim of this study was to evaluate the efficacy and safety of chemoradiotherapy (RCT) combined with regional deep hyperthermia (RHT) of high-risk bladder cancer after transurethral resection of bladder tumor (TUR-BT).Materials and ...
Bertz, Simone, Fietkau, Rainer, Gall, Christine, Haderlein, Marlen, Hartmann, Arndt, Keck, Bastian, Kühn, Reinhard, Merten, Ricarda, Ott, Oliver, Rödel, Claus Michael, Uter, Wolfgang, Weiss, Christian, Wullich, Bernd   +12 more
core  

Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications [PDF]

, 2016
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in ...
Bagshaw, S. M., Balducci, A., Baldwin, I., Barbarigo, F., Bellomo, R., Bellomo, Rinaldo, Braganã³, P., Braunsky, J., Calletti, F., Cerda, J., Cerda, Jorge, Chawla, L., De Gaudio, A. Raffaele, De Rosa, S., De Rosa, Silvia, Di Somma, S., Doi, K., Dosil Rosende, P., Emmett, M., Fecondini, L., Galavotti, D., Garzotto, F., Garzotto, Francesco, Gibney, N., Goldstein, S. L., Guadagni, G., Honore, Patrick M., Honorã, P., Hoste, E., Inadome, S., Kashani, K., Katz, N., Kellum, J., Kenley, R., Kobayashi, Y., Lannoy, J., Lewington, A., Lorenzin, Anna, Mariano, F., Mccullough, P. A., Mehta, R. L., Menneguerre, J., Mettifogo, M., Neri, M., Neri, Mauro, Ostermann, M., Pani, A., Payen, Didier, Pirazzoli, P., Pohlmeier, R., Pouchoulin, D., Ricci, Z., Ricci, Zaccaria, Ronco, C., Ronco, Claudio, Rosner, M., Samoni, Sara, Seamann, M., Shaw, A., Tolwani, A., Villa, G., Villa, Gianluca, Vincent, J. L., Vincent, Jean-Louis, Wendon, J., Wendon, Julia, Zaccaria, Marta   +66 more
core   +4 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

A CASE REPORT OF SUCCESSFUL TREATMENT OF STAGE IV ESOPHAGEAL CANCER

Сибирский онкологический журнал, 2019
Background. Esophageal cancer is among the ten most common cancers and causes-related mortality worldwide. Most patients present with an advanced stage tumor at diagnosis.
V. N. Khmelevskaya, P. A. Isaev, I. V. Gunko   +2 more
doaj   +1 more source