Results 51 to 60 of about 280,962 (297)

Research Progress of Pharmacological Therapy and Nutritional Support for Cachexia 
in Lung Cancer Patients

open access: yesChinese Journal of Lung Cancer, 2022
Cachexia is a common complication in patients with lung cancer. It aggravates the toxic and side effects of chemotherapy, hinders the treatment plan, weakens the responsiveness of chemotherapy, reduces the quality of life, increases complications and ...
Jiemin WANG   +7 more
doaj   +1 more source

Does cueing training improve physical activity in patients with Parkinson's disease? [PDF]

open access: yes, 2010
Patients with Parkinson’s disease (PD) are encouraged to stay active to maintain their mobility. Ambulatory activity monitoring (AM) provides an objective way to determine type and amount of gait-related daily activities.
Alice Nieuwboer   +9 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

A current perspective on stereotactic body radiation therapy for pancreatic cancer. [PDF]

open access: yes, 2016
Pancreatic cancer is a formidable malignancy with poor outcomes. The majority of patients are unable to undergo resection, which remains the only potentially curative treatment option.
Czito, Brian G   +3 more
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Papillary carcinoma of the thyroglossal cyst as a metastasis of microcarcinoma of thyroid cancer: a case report and literature review

open access: yesBrazilian Journal of Oncology, 2021
Papillary carcinoma of the thyroglossal cyst is clinically like the benign lesion in adults aged 15-45 year, with a higher incidence in females. It is a congenital anomaly of the midline of the neck and have the clinical worsening related to infections ...
Sergio Altino Franzi   +1 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Combination Therapies in Ophthalmology: Implications for Intravitreal Delivery

open access: yesJournal of Ophthalmic & Vision Research, 2011
Most pathological processes involve complex molecular pathways that can only be modified or blocked by a combination of medications. Combination therapy has become a common practice in medicine.
Gholam A Peyman, Kamran Hosseini
doaj  

Immune targets in the tumor microenvironment treated by radiotherapy. [PDF]

open access: yes, 2019
Radiotherapy (RT), the major anti-cancer modality for more than half of cancer patients after diagnosis, has the advantage of local tumor control with relatively less systematic side effects comparing to chemotherapy.
Li, Jian Jian   +2 more
core  

Comparing the effects of repetitive transcranial magnetic stimulation and electroconvulsive therapy in the treatment of depression : a systematic review and meta-analysis [PDF]

open access: yes, 2014
Electroconvulsive therapy (ECT) is the longest standing psychiatric treatment available and has unequivocal benefit in severe depression. However this treatment comes with a number of side effects such as memory impairment.
Micallef-Trigona, Beppe
core   +4 more sources

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