Results 111 to 120 of about 26,761 (295)

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Safety and tolerability of a combined oral contraceptive containing estetrol/drospirenone in real-life clinical practice: An open-label, prospective, multicenter, epidemiological, observational program "Estetiko"

Гинекология
Aim. To evaluate the safety and acceptability of a combined oral contraceptive (COC) containing estetrol 15 mg and drospirenone 3 mg when taken for 6 cycles in real clinical practice. Materials and methods. An open-label prospective multicenter (in 20
Natalia V. Aganezova, Rushania I. Gabidullina   +1 more
doaj   +1 more source

Identification of antibiotic allergies in children using prescribing patterns in the electronic medical record

British Journal of Clinical Pharmacology, EarlyView.
Background By age three, 5%–75% of children have a documented antibiotic allergy (AL). Despite this prevalence, recognition remains low because of limited clinician knowledge and time. Our study evaluates a novel approach to identifying AL using electronic medical record (EMR) prescription patterns.
Georgia Koutsaplis, Kailey Tang, Renee Dimond, Alice Lei, Amanda Wilkins, Amanda Gwee   +5 more
wiley   +1 more source

Combined Oral Contraceptives in Women with Systemic Lupus Erythematosus

, 2005
BACKGROUND Oral contraceptives are rarely prescribed for women with systemic lupus erythematosus, because of concern about potential negative side effects.
Belmont, H. Michael, Diamond, Betty, Sigler, Lisa, Hearth-Holmes, Michelene, Tan, Mark, Askanase, Anca D., Rupel, Ann, Kim, Mimi Y., Cronin, Mary, Dooley, Mary Anne, Fillius, Michael, Von Feldt, Joan, Davis, John, Kalunian, Kenneth C., Hahn, Bevra H., Petri, Michelle, Sammaritano, Lisa R., Buyon, Jill P., Licciardi, Frederick, McCune, W. Joseph, Merrill, Joan T., Friedman, Alan, Grossman, Jennifer, Lockshin, Michael, Mackay, Meggan   +24 more
core   +1 more source

Oseltamivir drug‐disease modelling in infants with influenza virus infection

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Oseltamivir is a commonly used neuraminidase inhibitor for treatment of influenza infection, but little data exist regarding concentration‐response relationships. Methods Pharmacokinetic (PK) and viral dynamic data from an earlier NIAID Collaborative Antiviral Study Group trial in paediatric patients with influenza from 0–23 months of age
Kun Wang, David W. Kimberlin, Richard J. Whitley, Edward P. Acosta, For the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group   +4 more
wiley   +1 more source

Combined oral contraceptives: the optimal range of examination. Part 1

, 2018
Combined oral contraceptives are effective drugs for contraception and treatment of reproductive disorders in polycystic ovarian syndrome. The article considers the main laboratory algorithms for excluding the most common endocrine diseases, the clinical
O.V. Rykova
core   +1 more source

Erwin Schrödinger und die Versuchungen der (Wissenschafts‐)Biografik: Vorurteilsgefüge und Mechanismen der Skandalisierung

Berichte zur Wissenschaftsgeschichte, EarlyView.
Since late 2021, serious allegations have been made against physicist Erwin Schrödinger, ranging from pedophilia to serial sexual abuse. These accusations have significantly tarnished the Nobel Prize winner's public reputation. The ongoing debate has repeatedly raised the question of whether, and to what extent, these grave allegations are justified ...
Magdalena Gronau, Martin Gronau
wiley   +1 more source

Oral contraceptives induced hepatotoxicity

, 2017
Oral Contraceptives are the pharmacological agents used to prevent pregnancy. These are divided as the combined and progestogen methods and are administered orally, transdermally, systemically and via vaginal route.
Srikanth, B. Akshaya, Manisree, V.
core  

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Combined Oral Contraceptives (Birth Control Pills)

This brochure explains what Combined Oral Contraceptives (COCs) are, how they work, their effectiveness, options, and other relevant information, and things to ...
South Carolina Department of Public Health
core   +1 more source