Results 131 to 140 of about 209,758 (346)

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

PrEP at the site of action in cisgender and transgender women: A pharmacology study of blood and rectal CD4+ lymphocytes

British Journal of Clinical Pharmacology, EarlyView.
Background Female sex hormones used in feminizing hormone therapy (FHT) may influence activation and persistence of HIV pre‐exposure prophylaxis (PrEP) medications. The clinical relevance of this interaction remains unclear, particularly for transgender and cisgender women (TGW and CGW).
Elizabeth Hastie, Megha Srivasta, Edward R. Cachay, Leah Burke, Sara Gianella, Stephen Rawlings, Frank Z. Stanczyk, Craig Sykes, Angela D. M. Kashuba, Jill Blumenthal, Mackenzie L. Cottrell   +10 more
wiley   +1 more source

URGENCY OF COMBINED ORAL CONTRACEPTIVES IN PROLONGED REGIMEN USE

Акушерство, гинекология и репродукция, 2016
This article presents the issues on combined oral contraceptives use in prolonged regimen.
A. L. Tikhomirov, A. A. Ledenkova
doaj  

Benefits of using combined oral contraceptive with drospirenone in 24+4 overweight adolescents [PDF]

Гинекология, 2014
Combined oral contraception is known as a reliable method of birth control that can provide additional benefits to health and quality of life . Reliability and the main characteristics of combined oral contraceptives do not differ significantly.
I V Kuznetsova, P A Nabiyeva
doaj  

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Postabortal rehabilitation – aspects of the problem: possibilities of combined oral contraceptives

Гинекология, 2013
The article presents modern concepts of pharmacological possibilities to use combined oral contraceptives for prevention of various postabortal complications, rational approaches of their use in female patients in postabortal period.
M B Khamoshina, I S Savelyeva, E A Zorina, M S Tulupova, T N Zulumyan   +4 more
doaj  

Combined oral contraceptives: evolution of the relationship benefit/risk

Безопасность и риск фармакотерапии, 2018
Currently, more than 100 million women worldwide use combined oral contraceptives. Risk/benefit ratio of this group of drugs over the half-century history is largely changed in the direction of safety.
O. S. Alyautdina
doaj  

Emergency Contraception for Adolescents [PDF]

, 2008
Healthy Teen Network recommends that emergency contraception be treated as any other over-the-counter drug by pharmacies and be available over-the-counter without a prescription to adolescents. We encourage teaching adolescents, their parents, and health

core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

When rare conditions collide: plantar vein thrombosis in hereditary spherocytosis

Journal of the Foot & Ankle
Plantar heel pain is a common orthopedic complaint, but less frequent etiologies like plantar vein thrombosis (PVT) are often overlooked. We present the case of a 27-year-old female with a history of hereditary spherocytosis who developed left plantar ...
Budak Akman, Behic Celik, Betul Uzunoglu
doaj   +3 more sources