Results 171 to 180 of about 2,423,331 (345)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Diallel cross analysis of traits related to growth and survival of ornamental fish (Puntius tetrazona)

open access: yes‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, 2015
Intra species hybridizations have been extensively used to produce varieties with superior characteristics for use in aquatic animals. In this study, maternal effects, general and specific combining ability, heterosis and inbreeding depression of growth ...
Hossein Akbari; Gholam Reza Dashab email
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Combining Ability and Reciprocal Effects for the Yield of Elite Blue Corn Lines from the Central Highlands of Mexico. [PDF]

open access: yesPlants (Basel), 2023
Arellano-Vázquez JL   +6 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Combining ability as a strategy for selecting common bean parents and populations resistant to white mold

open access: gold, 2018
Lenio Urzeda Ferreira   +6 more
openalex   +1 more source

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