Results 71 to 80 of about 378,621 (297)

Model‐informed precision dosing of carboplatin in cancer patients by leveraging myelosuppression data from electronic health records

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This study aimed to develop and validate a population pharmacokinetic‐pharmacodynamic (pop‐PK‐PD) model to describe carboplatin‐induced myelosuppression in cancer patients and support dose individualization. Methods Data from 580 cancer patients treated with carboplatin at Amsterdam UMC between 2019 and 2022 were used for model ...
Alessandro De Carlo, Elena Maria Tosca, Mirjam Crul, Tim Schutte, Lia van Zuijlen, Idris Bahce, Medhat M. Said, Jan Buter, Harmen Huls, Paolo Magni, Imke Bartelink   +10 more
wiley   +1 more source

Cringe Overhang: The Perlocutionary Effects of Cringe Comedy

European Journal of Analytic Philosophy
Cringe comedy can make people so uncomfortable, the cringe continues even after the comedy has stopped. This paper explains this effect, which I call “cringe overhang”. If audiences weakly connect to the characters, they laugh.
Alexander Sparrow
doaj   +1 more source

Definitions of the humorous in Chris Rock and Russell Peters fan blogs: A discussion of the problem of incongruity [PDF]

, 2011
There is an old and unsolved problem in the philosophy of humour that examines the conditions under which some incongruities are deemed funny and some are not.
Weaver, S
core  

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Making it explicit – Sustained shared thinking dialogue as a way to explore children's perspectives on quality in German early childhood education and care

British Educational Research Journal, EarlyView.
Abstract To negotiate quality in early childhood education and care, we must ask from different perspectives what constitutes a good centre for children. The children themselves have only recently been identified as a resource to contribute to that discussion.
Katrin Macha, Frauke Hildebrandt, Caroline Wronski, Jan Lonnemann, Mathias Urban   +4 more
wiley   +1 more source

The Meaning of Slang Language in 22 Jump Street Movie [PDF]

, 2015
This research focused on the meaning of slang language used by the characters in 22Jump Street Movie. The research was conducted by using qualitative method. Thedata were collected from the movie script.
Pulungan, E. J. (Eren)
core  

The Work of Tragic Productions: Towards a New History of Drama as Labor Culture [PDF]

, 2014
Preliminary analysis of the representation of laborers in Greek tragedy and satyr ...
David Roselli
core   +1 more source

Making teaching an attractive profession: What are the challenges and opportunities for minority ethnic teachers in England?

British Educational Research Journal, EarlyView.
Abstract This paper explores the challenges and opportunities surrounding the recruitment and retention of minority ethnic teachers in England. Drawing on interview data from 33 teachers and school leaders of diverse ethnic backgrounds, it investigates whether racialised barriers identified in earlier research have shifted in the current context of ...
Antonina Tereshchenko, Feyisa Demie, Stephen Gorard, Yiyang Gao, Beng Huat See, Nadia Siddiqui   +5 more
wiley   +1 more source

"'Most People Bring Their Own Spoons': THE ROOM's participatory audiences as comedy mediators" [PDF]

, 2011
THE ROOM (Tommy Wiseau, 2003) has developed the unenviable reputation as being one of the worst films ever made, yet at the same time is celebrated by ‘fans’ who take considerable pleasure from its perceived ineptitude.
McCulloch, Richard
core  

Improving the learning experience in an undergraduate course on microbial metabolism by using an illustrated story

Biochemistry and Molecular Biology Education, Volume 53, Issue 2, Page 131-141, March/April 2025.
Abstract In the classroom, metabolism is often approached and received as a mundane exercise in memorization. Teaching metabolism also faces the challenge of negative perceptions that can impede learning. We sought to improve the learning experience in an undergraduate lecture course on microbial metabolism by implementing an illustrated story that ...
James B. McKinlay, Katherine Kearns
wiley   +1 more source