Results 131 to 140 of about 58,125 (347)

Comet and micronucleus assays do not correlate extent of DNA damage with clinical staging of oral cavity squamous cell carcinoma [PDF]

open access: diamond, 2020
Andreza Negreli Santos   +7 more
openalex   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

Outcomes of periodontal therapy: Strengthening the relevance of research to patients. A co‐created review

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontitis is a long‐term condition affecting up to half of the population globally and causing significant impacts on life quality. Successful management depends on taking life‐long ownership of the condition by those affected. There is a wealth of research to inform on management options. However, most of the research has been designed by
Ian Needleman   +3 more
wiley   +1 more source

Citogenotoxic response of juvenile cobia Rachycentron canadum (Linnaeus, 1766) reared in two different systems

open access: yesBrazilian Journal of Oceanography
Aquaculture production is continuously growing worldwide, and marine fish farming in Brazil is still in its infancy. Intensive farming conditions may cause physiological stress to the cultured organism, which can be evaluated by citogenotoxic biomarkers.
Marina Tenório Botelho   +7 more
doaj   +1 more source

The application of comet assay in monitoring of the immunosuppression level in a patient with toxic epidermal necrolysis: A case report

open access: yesBurns Open, 2017
Toxic epidermal necrolysis (TEN) represents the most serious affection within the SCARs group (Severe Cutaneous Adverse Reactions). It is an autoimmune disease manifested by extensive epidermal and mucosal exfoliation.
B. Lipový   +8 more
doaj   +1 more source

Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley   +1 more source

The comet assay – how to recognise “good data”

open access: yesFrontiers in Genetics, 2015
Testing of potentially genotoxic materials currently involves use of in vitro assays such as the Ames test (gene mutations), the chromosome aberration assay and in vitro micronucleus assay (predominantly using human peripheral lymphocytes to detect ...
William Barfield
doaj   +1 more source

Types of Pain in Multiple System Atrophy

open access: yesMovement Disorders, EarlyView.
Abstract Background Pain affects up to 87% of people with multiple system atrophy (MSA), but it remains unclear which types of pain contribute most to the overall burden. Objective To estimate the frequency of different types of pain in MSA individuals.
Nicole Campese   +19 more
wiley   +1 more source

The ability of the Comet assay to discriminate between genotoxins and cytotoxins [PDF]

open access: bronze, 1998
L.M. Henderson   +4 more
openalex   +1 more source

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